Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …

Recent studies have discovered that tiny particles of microplastics (MPs) at the nano-scale
level can enter the body of organisms from the environment, potentially causing metabolic …

Purpose An increasing amount of evidence suggests that psoriasis and nonalcoholic
steatohepatitis (NASH) may occur simultaneously, whereas the underlying mechanisms …

Interferon regulatory factors (IRFs) comprise a family of nine transcription factors in
mammals. IRFs exert broad effects on almost all aspects of immunity but are best known for …

Metabolic dysfunction-associated steatohepatitis (MASH) is the replacement term for what
used to be called nonalcoholic steatohepatitis (NASH). It is characterized by inflammation …

Objective The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor
regulating xenobiotic responses as well as physiological metabolism. Dietary AhR ligands …

Background Non-alcoholic steatohepatitis (NASH) is a rapidly progressing chronic liver
disease of global significance. However, the underlying mechanisms responsible for NASH …

Non-alcoholic fatty liver disease (NAFLD) is a prevalent liver disorder with significant health
implications. N6-methyladenosine (m6A) methyltransferase is known to exert regulatory …

keto-PGE 2 is one of the eicosanoids with anti-inflammatory properties. In this study, we
demonstrated that 15-keto-PGE 2 post-translationally modified the nuclear factor κ-light …