Cadmium toxicity: effects on human reproduction and fertility

S Kumar, A Sharma - Reviews on environmental health, 2019 - degruyter.com
Abstract Background Cadmium (Cd) is a non-essential toxic heavy metal, an environmental
toxicant, and toxic at a low concentration, and it has no known beneficial role in the human …

[HTML][HTML] Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention

L Chen, G Shi, D Huang, Y Li, C Ma, M Shi, B Su… - Biomedicine & …, 2019 - Elsevier
Sexual dysfunction (SD) is a disorder of sexual behavior and sexual sensation that appears
as an abnormality or absence of sexual psychology and physiological reaction. It is a …

Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

[HTML][HTML] Exposure to low-dose cadmium induces testicular ferroptosis

L Xiong, B Zhou, JL Young, K Wintergerst… - … and environmental safety, 2022 - Elsevier
As an environmental pollutant, cadmium (Cd) has been widely reported to induce male
infertility due to its gonadotoxicity. However, the specific mechanism of Cd-induced testicular …

Improvement of testicular steroidogenesis using flavonoids and isoflavonoids for prevention of late-onset male hypogonadism

LJ Martin, M Touaibia - Antioxidants, 2020 - mdpi.com
Androgen production, being important for male fertility, is mainly accomplished by the Leydig
cells from the interstitial compartment of the testis. Testosterone plays a critical role in testis …

[PDF][PDF] Potential therapeutic use of plant flavonoids in AD and PD

S Meng-Zhen, L Ju, Z Lan-Chun, D Cai-Feng… - Heliyon, 2022 - cell.com
Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …

Potential role of quercetin in polycystic ovary syndrome and its complications: A review

T Chen, F Jia, Y Yu, W Zhang, C Wang, S Zhu, N Zhang… - Molecules, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive,
metabolic and psychological abnormalities. It is characterized by a high prevalence rate in …

Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats

J Wang, H Zhu, S Lin, K Wang, H Wang, Z Liu - Journal of Inorganic …, 2021 - Elsevier
This study aimed to investigate the effect of naringenin (Nar) on cadmium (Cd)-induced
testicular toxicity. Twenty-four male Sprague–Dawley (SD) rats aged 5 weeks were used …

Pharmacological action of quercetin against testicular dysfunction: A mini review

DE Rotimi, TD Olaolu, OS Adeyemi - Journal of Integrative Medicine, 2022 - Elsevier
The testis is an immune-privileged organ susceptible to oxidative stress and inflammation,
two major factors implicated in male infertility. A reduction in the concentration and activities …

Pharmacological activity of flavonoid quercetin and its therapeutic potential in testicular injury

X Zhang, Y Tang, G Lu, J Gu - Nutrients, 2023 - mdpi.com
Quercetin is a natural flavonoid widely found in natural fruits and vegetables. Recent studies
have shown that quercetin mediates multiple beneficial effects in a variety of organ damage …