The human virome: assembly, composition and host interactions
G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …
known is the fact that the human body also hosts vast numbers of different viruses …
Agnostic sequencing for detection of viral pathogens
NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …
detect and analyze microbial genomes and has yielded novel molecular approaches for …
[HTML][HTML] Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus
Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …
and progression of Alzheimer's disease (AD) although definitive evidence has not been …
VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data
Background Identifying viral sequences in mixed metagenomes containing both viral and
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
Identifying viruses from metagenomic data using deep learning
J Ren, K Song, C Deng, NA Ahlgren… - Quantitative …, 2020 - Wiley Online Library
Background The recent development of metagenomic sequencing makes it possible to
massively sequence microbial genomes including viral genomes without the need for …
massively sequence microbial genomes including viral genomes without the need for …
The human intestinal virome in health and disease
SR Carding, N Davis, L Hoyles - Alimentary pharmacology & …, 2017 - Wiley Online Library
Background The human virome consists of animal‐cell viruses causing transient infections,
bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and …
bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and …
Beyond just bacteria: functional biomes in the gut ecosystem including virome, mycobiome, archaeome and helminths
Gut microbiota refers to a complex network of microbes, which exerts a marked influence on
the host's health. It is composed of bacteria, fungi, viruses, and helminths. Bacteria, or …
the host's health. It is composed of bacteria, fungi, viruses, and helminths. Bacteria, or …
The gut virome: the 'missing link'between gut bacteria and host immunity?
I Mukhopadhya, JP Segal, SR Carding… - Therapeutic …, 2019 - journals.sagepub.com
The human gut virome includes a diverse collection of viruses that infect our own cells as
well as other commensal organisms, directly impacting on our well-being. Despite its …
well as other commensal organisms, directly impacting on our well-being. Despite its …
Human virome and disease: high-throughput sequencing for virus discovery, identification of phage-bacteria dysbiosis and development of therapeutic approaches …
TM Santiago-Rodriguez, EB Hollister - Viruses, 2019 - mdpi.com
The virome is comprised of endogenous retroviruses, eukaryotic viruses, and
bacteriophages and is increasingly being recognized as an essential part of the human …
bacteriophages and is increasingly being recognized as an essential part of the human …
Necrotizing enterocolitis is preceded by increased gut bacterial replication, Klebsiella, and fimbriae-encoding bacteria
Necrotizing enterocolitis (NEC) is a devastating intestinal disease that occurs primarily in
premature infants. We performed genome-resolved metagenomic analysis of 1163 fecal …
premature infants. We performed genome-resolved metagenomic analysis of 1163 fecal …