Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity

A Penesyan, IT Paulsen, S Kjelleberg… - npj Biofilms and …, 2021 - nature.com
Biofilms are organised heterogeneous assemblages of microbial cells that are encased
within a self-produced matrix. Current estimates suggest that up to 80% of bacterial and …

Microbial surface colonization and biofilm development in marine environments

H Dang, CR Lovell - Microbiology and molecular biology reviews, 2016 - Am Soc Microbiol
Biotic and abiotic surfaces in marine waters are rapidly colonized by microorganisms.
Surface colonization and subsequent biofilm formation and development provide numerous …

Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections

C Winstanley, S O'Brien, MA Brockhurst - Trends in microbiology, 2016 - cell.com
Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

Filamentous bacteriophage promote biofilm assembly and function

PR Secor, JM Sweere, LA Michaels, AV Malkovskiy… - Cell host & …, 2015 - cell.com
Biofilms—communities of bacteria encased in a polymer-rich matrix—confer bacteria with
the ability to persist in pathologic host contexts, such as the cystic fibrosis (CF) airways. How …

Rapid microevolution of biofilm cells in response to antibiotics

A Penesyan, SS Nagy, S Kjelleberg… - NPJ biofilms and …, 2019 - nature.com
Infections caused by Acinetobacter baumannii are increasingly antibiotic resistant,
generating a significant public health problem. Like many bacteria, A. baumannii adopts a …

Evolution of antibiotic resistance in biofilm and planktonic Pseudomonas aeruginosa populations exposed to subinhibitory levels of ciprofloxacin

MN Ahmed, A Porse, MOA Sommer… - Antimicrobial agents …, 2018 - Am Soc Microbiol
The opportunistic Gram-negative pathogen Pseudomonas aeruginosa, known for its intrinsic
and acquired antibiotic resistance, has a notorious ability to form biofilms, which often …

Experimental evolution in biofilm populations

HP Steenackers, I Parijs, KR Foster… - FEMS microbiology …, 2016 - academic.oup.com
Biofilms are a major form of microbial life in which cells form dense surface associated
communities that can persist for many generations. The long-life of biofilm communities …

A filamentous bacteriophage protein inhibits type IV pili to prevent superinfection of Pseudomonas aeruginosa

AK Schmidt, AD Fitzpatrick, CM Schwartzkopf, DR Faith… - MBio, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of
settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage …

Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria

AK Tarafder, A von Kügelgen… - Proceedings of the …, 2020 - National Acad Sciences
The opportunistic pathogen Pseudomonas aeruginosa is a major cause of antibiotic-tolerant
infections in humans. P. aeruginosa evades antibiotics in bacterial biofilms by up-regulating …

Pf bacteriophage and their impact on Pseudomonas virulence, mammalian immunity, and chronic infections

PR Secor, EB Burgener, M Kinnersley… - Frontiers in …, 2020 - frontiersin.org
Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa,
a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and …