Molecular mechanisms of hematological and biochemical alterations in malaria: a review

IU Okagu, RN Aguchem, CA Ezema… - Molecular and …, 2022 - Elsevier
Malaria is a dangerous disease that contributes to millions of hospital visits and hundreds of
thousands of deaths, especially in children residing in sub-Saharan Africa. Although several …

[HTML][HTML] Resistance status of Anopheles gambiae (sl) to four commonly used insecticides for malaria vector control in South-East Nigeria

O Chukwuekezie, E Nwosu, U Nwangwu, F Dogunro… - Parasites & vectors, 2020 - Springer
Background Progress made in the control of malaria vectors globally is largely due to the
use of insecticides. However, success in the fight against malaria has slowed down or even …

[HTML][HTML] Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii

SS Ibrahim, A Muhammad, J Hearn, GD Weedall… - BMC biology, 2023 - Springer
Background Information on common markers of metabolic resistance in malaria vectors from
countries sharing similar eco-climatic characteristics can facilitate coordination of malaria …

[HTML][HTML] A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from …

AN Fadel, SS Ibrahim, M Tchouakui, E Terence… - Parasites & vectors, 2019 - Springer
Background The scale-up in the distribution of long-lasting insecticidal nets (LLINs) and
indoor residual spraying has significantly reduced malaria burden and mortality. However …

[HTML][HTML] High pyrethroid/DDT resistance in major malaria vector Anopheles coluzzii from Niger-Delta of Nigeria is probably driven by metabolic resistance …

A Muhammad, SS Ibrahim, MM Mukhtar, H Irving… - PLoS …, 2021 - journals.plos.org
Entomological surveillance of local malaria vector populations is an important component of
vector control and resistance management. In this study, the resistance profile and its …

Insecticide Resistance Profile of Anopheles gambiae Mosquitoes: A Study of a Residential and Industrial Breeding Sites in Kano Metropolis, Nigeria

CJ Ononamadu, JT Datit… - Environmental Health …, 2020 - journals.sagepub.com
Monitoring and understanding the trend and dynamics of insecticide resistance is very key to
devising efficient control strategies. This study was carried out to characterize the mosquito …

Emerging mosquito resistance to piperonyl butoxide-synergized pyrethroid insecticide and its mechanism

G Zhou, Y Li, B Jeang, X Wang… - Journal of medical …, 2022 - academic.oup.com
Piperonyl butoxide (PBO)-synergized pyrethroid products are widely available for the control
of pyrethroid-resistant mosquitoes. To date, no study has examined mosquito resistance …

High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic

SS Ibrahim, AN Fadel, M Tchouakui… - Infectious Diseases of …, 2019 - mednexus.org
Background: The Sahel region of Chad Republic is a prime candidate for malaria pre-
elimination. To facilitate pre-elimination efforts in this region, two populations of Anopheles …

The cytochrome P450 CYP325A is a major driver of pyrethroid resistance in the major malaria vector Anopheles funestus in Central Africa

ANR Wamba, SS Ibrahim, MO Kusimo… - Insect Biochemistry and …, 2021 - Elsevier
The overexpression and overactivity of key cytochrome P450s (CYP450) genes are major
drivers of metabolic resistance to insecticides in African malaria vectors such as Anopheles …

[HTML][HTML] Absence of knockdown mutations in pyrethroid and DDT resistant populations of the main malaria vectors in Colombia

LI Orjuela, DA Álvarez-Diaz, JA Morales, N Grisales… - Malaria Journal, 2019 - Springer
Background Knockdown resistance (kdr) is a well-characterized target-site insecticide
resistance mechanism that is associated with DDT and pyrethroid resistance. Even though …