Flaviviruses have evolved complex mechanisms to evade the mammalian host immune
systems including the RIG-I (retinoic acid-inducible gene I) like receptor (RLR) signaling …

In the last years, proteomics has represented a valuable approach to elucidate key aspects
in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved …

The immune system protects the organism against infections and the damage associated
with them. The first line of defense against pathogens is the innate immune response. In the …

Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

Dengue virus (DENV) is the etiological agent of dengue fever. Severe dengue could be fatal
and there is currently no effective antiviral agent or vaccine. The only licensed vaccine …

Toll‐like receptors (TLRs) are important sensors that recognize pathogen‐associated
molecular patterns. Generally, TLR9 is known to recognize bacterial or viral DNA but not …

Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …

Flaviviruses comprise a genus of viruses that pose a significant burden on human health
worldwide. Transmission by both mosquito and tick vectors, and broad host tropism …

ABSTRACT DNA damage-inducible transcript 3 (DDIT3) plays important roles in
endoplasmic reticulum (ER) stress-induced apoptosis and autophagy, but its role in innate …

The Zika virus (ZIKV) is a recently emerged mosquito-borne flavivirus that, while typically
asymptomatic, can cause neurological symptoms in adults and birth defects in babies born …