Japanese encephalitis virus (JEV) is a mosquito-borne Flavivirus that causes severe
neurologic disease in humans. NS1′ is a NS1-related protein only reported in the …

Zika virus (ZIKV) is a mosquito-transmitted flavivirus that caused a public health emergency
in the Americas when an outbreak in Brazil became linked to congenital microcephaly …

Dengue virus (DENV) is a widespread arbovirus. To efficiently establish infection, DENV
evolves multiple strategies to hijack the host innate immune response. Herein, we examined …

The ongoing concurrent outbreaks of Zika, Chikungunya, and dengue viruses in Latin
America and the Caribbean highlight the need for development of broad-spectrum antiviral …

Dengue is a worldwide disease with 400 million annual infections that can lead to septic
shock and viral hemorrhagic fever with internal bleeding. These symptoms are the result of …

Dengue is potentially a life-threatening arthropod-borne viral infection for which there are no
known therapeutic agents till date. Early stage diagnosis of dengue infection is still lacking …

Intracellular DNA and RNA sensors play a vital part in the innate immune response to
viruses and other intracellular pathogens, causing the secretion of type I interferons …

Mitochondrial antiviral signaling protein (MAVS), also known as IPS-1, VISA, and Cardif, has
been well studied for its crucial roles in the mammalian interferon immune response. To …

MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in regulating the
host immune response. Here we found that miR-22 is induced in glial cells upon stimulation …

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic
fever/dengue shock syndrome. At present, no antiviral drugs are available for treatment …