Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular …
JN Tian, RH Wu, SL Chen… - Journal of General …, 2019 - microbiologyresearch.org
The NS4A protein of dengue virus (DENV) has a cytosolic N terminus and four
transmembrane domains. NS4A participates in RNA replication and the host antiviral …
transmembrane domains. NS4A participates in RNA replication and the host antiviral …
[HTML][HTML] 非洲猪瘟病毒MGF360-14L 靶向MAVS 抑制Ⅰ 型干扰素的产生
王洋， 崔帅， 鑫婷， 王西西， 于海男， 陈世钰， 蒋亚君… - 畜牧兽医学报, 2022 - xml-data.org
本研究旨在探究非洲猪瘟病毒(African swine fever virus, ASFV) 多基因家族成员MGF360-14L
对Ⅰ 型干扰素(IFN) 的抑制作用及其作用机制. 通过双荧光素酶试验检测MGF360-14L …
对Ⅰ 型干扰素(IFN) 的抑制作用及其作用机制. 通过双荧光素酶试验检测MGF360-14L …
Cross Talk between MicroRNAs and Dengue Virus.
NO Macha, TV Komarasamy, S Harun… - The American Journal …, 2024 - europepmc.org
Dengue fever (DF) is an endemic infectious tropical disease and is rapidly becoming a
global problem. Dengue fever is caused by one of the four dengue virus (DENV) serotypes …
global problem. Dengue fever is caused by one of the four dengue virus (DENV) serotypes …
Interaction between NS1 and cellular MAVS contributes to NS1 mitochondria targeting
YY Tseng, CY Kuan, M Mibayashi, CJ Chen, P Palese… - Viruses, 2021 - mdpi.com
Influenza A virus nonstructural protein 1 (NS1) plays an important role in evading host innate
immunity. NS1 inhibits interferon (IFN) responses via multiple mechanisms, including …
immunity. NS1 inhibits interferon (IFN) responses via multiple mechanisms, including …
Tumour‐associated macrophages as a novel target of VEGI‐251 in cancer therapy
X Dong, X Huang, Z Yao, Y Wu, D Chen… - Journal of Cellular …, 2020 - Wiley Online Library
Abstract Tumour‐associated macrophages (TAMs), which possess M2‐like characters and
are derived from immature monocytes in the circulatory system, represent a predominant …
are derived from immature monocytes in the circulatory system, represent a predominant …
Assessment of prolonged dengue virus infection in dermal fibroblasts and hair-follicle dermal papilla cells
Dengue virus (DENV)-mediated hair loss is one of the post-dengue fatigue syndromes and
its pathophysiology remains unknown. Whether long-term or persistent infection with DENV …
its pathophysiology remains unknown. Whether long-term or persistent infection with DENV …
A novel in vivo model of Zika virus infection unveils NS4A as a key determinant of neuropathogenesis
L Chatel-Chaix, AA Sow, P Priyanka Jamadagni… - bioRxiv, 2024 - biorxiv.org
Infection of pregnant women by Zika virus (ZIKV) is associated with severe
neurodevelopmental defects in newborns through poorly defined mechanisms. Here, we …
neurodevelopmental defects in newborns through poorly defined mechanisms. Here, we …
[PDF][PDF] 基于登革病毒免疫逃逸机制的小鼠感染模型研究进展
李怡然， 师长宏， 赵勇， 吕玉红， 张彩勤 - 中国实验动物学报, 2023 - zgbjyx.cnjournals.com
登革病毒(dengue virus, DENV) 感染是世界上虫媒传播最广的病毒性疾病,
感染人体后可出现轻型和严重程度不同的登革热疾病进程. 由于DENV 主要通过抵抗人干扰素 …
感染人体后可出现轻型和严重程度不同的登革热疾病进程. 由于DENV 主要通过抵抗人干扰素 …
Zika virus NS4A hijacks host ANKLE2 to promote viral replication
AT Fishburn, MW Kenaston, NJ Lopez, V Hoang… - bioRxiv, 2022 - biorxiv.org
Zika virus (ZIKV) is infamous among flaviviruses for its unique association with congenital
birth defects, notably microcephaly. We previously mapped ZIKV-host protein interactions …
birth defects, notably microcephaly. We previously mapped ZIKV-host protein interactions …
[HTML][HTML] Selective dysfunction of subsets of peripheral blood mononuclear cells during pediatric dengue and its relationship with clinical outcome
F Perdomo-Celis, DM Salgado, CF Narváez - Virology, 2017 - Elsevier
During dengue virus (DENV) infection, a blockage of secretion of cytokines such as tumor
necrosis factor (TNF)-α and members of the interferon (IFN) family has been described in …
necrosis factor (TNF)-α and members of the interferon (IFN) family has been described in …