It has been known for approximately 30 years that large doses of the semi-essential basic
amino acid L-arginine induce severe pancreatic inflammation in rats. Recently, it has been …

Animal models are ideal to study the pathomechanism and therapy of acute pancreatitis
(AP). The use of L-arginine-induced AP model is nowadays becoming increasingly popular …

Aims Pancreatitis is characterized by inflammatory disease with severe tissue injury in
pancreas, and the incidence of pancreatitis has been recently increasing. Although several …

Mild injury of the exocrine pancreas is often asymptomatic and can be under-or mis-
diagnosed. The pancreas-enriched microRNAs miR-216a and miR-217 were evaluated as …

Patients suffering from severe acute pancreatitis (AP) can develop acute lung injury (ALI)
with poor outcomes and the mechanisms involved remain incompletely understood …

Background and Purpose Thrombopoietin (TPO), a growth factor primarily involved in
thrombopoiesis may also have a role in the pathophysiology of sepsis. In patients with …

Acute pancreatitis (AP)‑associated lung injury (ALI) is a critical complication of AP. Adropin
is a regulatory protein of immune metabolism. The present study aimed to explore the …

Objectives: Mesenchymal stem cells (MSCs) have shown an obvious protective effect on
systemic inflammation. The purpose of this study is to assess the effect and possible …

BACKGROUND Thrombopoietin (TPO) is a primary regulator of thrombopoiesis in
physiological conditions. TPO, in combination with its specific cytokine receptor c-Mpl, drives …

Objectives: Granny Smith is a cultivated hybrid variety of apple with a high antioxidant
content relative to all other species of apple. Acute pancreatitis (AP) is an instantly emerging …