[HTML][HTML] Big data approaches to decomposing heterogeneity across the autism spectrum

MV Lombardo, MC Lai, S Baron-Cohen - Molecular psychiatry, 2019 - nature.com
Autism is a diagnostic label based on behavior. While the diagnostic criteria attempt to
maximize clinical consensus, it also masks a wide degree of heterogeneity between and …

[HTML][HTML] Artificial intelligence for precision medicine in neurodevelopmental disorders

M Uddin, Y Wang, M Woodbury-Smith - NPJ digital medicine, 2019 - nature.com
The ambition of precision medicine is to design and optimize the pathway for diagnosis,
therapeutic intervention, and prognosis by using large multidimensional biological datasets …

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder

RK C Yuen, D Merico, M Bookman, JL Howe… - Nature …, 2017 - nature.com
We are performing whole-genome sequencing of families with autism spectrum disorder
(ASD) to build a resource (MSSNG) for subcategorizing the phenotypes and underlying …

[HTML][HTML] Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies

DJ Stein, P Szatmari, W Gaebel, M Berk, E Vieta, M Maj… - BMC medicine, 2020 - Springer
An update of the chapter on Mental, Behavioral and Neurodevelopmental Disorders in the
International Classification of Diseases and Related Health Problems (ICD) is of great …

[HTML][HTML] White matter alterations in Attention-Deficit/Hyperactivity Disorder (ADHD): a systematic review of 129 diffusion imaging studies with meta-analysis

V Parlatini, T Itahashi, Y Lee, S Liu, TT Nguyen… - Molecular …, 2023 - nature.com
Aberrant anatomical brain connections in attention-deficit/hyperactivity disorder (ADHD) are
reported inconsistently across diffusion weighted imaging (DWI) studies. Based on a pre …

Toward neurosubtypes in autism

SJ Hong, JT Vogelstein, A Gozzi, BC Bernhardt… - Biological …, 2020 - Elsevier
There is a consensus that substantial heterogeneity underlies the neurobiology of autism
spectrum disorder (ASD). As such, it has become increasingly clear that a dissection of …

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

M Hoogman, D Van Rooij, M Klein… - Human brain …, 2022 - Wiley Online Library
Neuroimaging has been extensively used to study brain structure and function in individuals
with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over …

[HTML][HTML] Examining overlap and homogeneity in ASD, ADHD, and OCD: a data-driven, diagnosis-agnostic approach

A Kushki, E Anagnostou, C Hammill, P Duez… - Translational …, 2019 - nature.com
The validity of diagnostic labels of autism spectrum disorder (ASD), attention-
deficit/hyperactivity disorder (ADHD), and obsessive compulsive disorder (OCD) is an open …

[HTML][HTML] Identify aberrant white matter microstructure in ASD, ADHD and other neurodevelopmental disorders: A meta-analysis of diffusion tensor imaging studies

Y Zhao, L Yang, G Gong, Q Cao, J Liu - Progress in Neuro …, 2022 - Elsevier
Abstract Background Neurodevelopmental disorders (NDDs) usually present overlapping
symptoms. Abnormal white matter (WM) microstructure has been found in these disorders …

Functional and structural brain network development in children with attention deficit hyperactivity disorder

SM Soman, N Vijayakumar, P Thomson… - Human Brain …, 2023 - Wiley Online Library
Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood neurodevelopmental
disorder. Given the profound brain changes that occur during childhood and adolescence, it …