Gliomas are aggressive, primary central nervous system tumours arising from glial cells.
Glioblastomas are the most malignant. They are known for their poor prognosis or median …

Oncolytic viral (OV) therapies are promising novel treatment modalities for cancers refractory
to conventional treatment, such as glioblastoma, within the central nervous system (CNS) …

Rationale: The resistance of pancreatic ductal adenocarcinoma (PDAC) to immunotherapies
is caused by the immunosuppressive tumor microenvironment (TME) and dense …

Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …

Stimulating the innate immune system has been explored as a therapeutic option for the
treatment of gliomas. Inactivating mutations in ATRX, defining molecular alterations in IDH …

Promises of oncolytic viral therapy for adult and children w... : Current Opinion in Oncology
Promises of oncolytic viral therapy for adult and children with brain glioma : Current Opinion …

Oncolytic virus ablation of tumor cells has the advantages of high tumor selectivity, strong
immunogenicity, and low side effects. However, the recognition and clearance of oncolytic …

Oncolytic viruses (OVs) have emerged as a clinical therapeutic modality potentially effective
for cancers that evade conventional therapies, including central nervous system …

The tumor suppressor gene PTEN (phosphatase and tensin homolog on chromosome 10)
encodes a lipid and protein phosphatase that antagonizes the oncogenic PI3K/AKT …

Glioma is the most common primary brain tumor. Filamin-binding LIM protein 1 (FBLIM1) has
been identified in multiple cancers and is suspected of playing a part in the development of …