miRNAs as potential game-changers in melanoma: a comprehensive review

GM Abd-Allah, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …

The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy

MB Zaki, AI Abulsoud, SS Elshaer, D Fathi… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular
carcinoma, has been rising worldwide in recent epidemiological research. This neoplasia's …

miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

Role of long non-coding RNAs in pancreatic cancer pathogenesis and treatment resistance-A review

TM Al-Noshokaty, A Mansour, R Abdelhamid… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) is one of the deadliest cancers associated with poor prognosis. The
lack of reliable means of early cancer detection contributes to this disease's dismal …

miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses

MS Elballal, AAM Sallam, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …

miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

Long non-coding RNAs and rheumatoid arthritis: Pathogenesis and clinical implications

O Elazazy, HM Midan, RK Shahin, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) are a class of noncoding RNAs with a length larger than
200 nucleotides that participate in various diseases and biological processes as they can …

A spotlight on the interplay of signaling pathways and the role of miRNAs in osteosarcoma pathogenesis and therapeutic resistance

AS Doghish, M Hegazy, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses

HA El-Mahdy, AM Mohamadin, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance-A focus on signaling pathways interplay

M Hegazy, MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Laryngeal cancer (LC) is the malignancy of the larynx (voice box). The majority of LC are
squamous cell carcinomas. Many risk factors were reported to be associated with LC as …