Molecular characterization of the missing electron pathways for butanol synthesis in Clostridium acetobutylicum

C Foulquier, A Rivière, M Heulot, S Dos Reis… - Nature …, 2022 - nature.com
Clostridium acetobutylicum is a promising biocatalyst for the renewable production of n-
butanol. Several metabolic strategies have already been developed to increase butanol …

Acetone–butanol–ethanol production with high productivity using Clostridium acetobutylicum BKM19

YS Jang, A Malaviya, SY Lee - Biotechnology and …, 2013 - Wiley Online Library
Conventional acetone–butanol–ethanol (ABE) fermentation is severely limited by low
solvent titer and productivities. Thus, this study aims at developing an improved Clostridium …

Biobutanol production in a Clostridium acetobutylicum biofilm reactor integrated with simultaneous product recovery by adsorption

D Liu, Y Chen, FY Ding, T Zhao, JL Wu, T Guo… - Biotechnology for …, 2014 - Springer
Background Clostridium acetobutylicum can propagate on fibrous matrices and form biofilms
that have improved butanol tolerance and a high fermentation rate and can be repeatedly …

Enhanced butanol production in Clostridium acetobutylicum ATCC 824 by double overexpression of 6-phosphofructokinase and pyruvate kinase genes

JRS Ventura, H Hu, D Jahng - Applied microbiology and biotechnology, 2013 - Springer
This study elucidated the importance of two critical enzymes in the regulation of butanol
production in Clostridium acetobutylicum ATCC 824. Overexpression of both the 6 …

Metabolic engineering of microorganisms for the production of higher alcohols

YJ Choi, J Lee, YS Jang, SY Lee - MBio, 2014 - Am Soc Microbiol
Due to the increasing concerns about limited fossil resources and environmental problems,
there has been much interest in developing biofuels from renewable biomass. Ethanol is …

Metabolic Engineering of Clostridium cellulovorans to Improve Butanol Production by Consolidated Bioprocessing

Z Wen, R Ledesma-Amaro, M Lu, M Jin… - ACS synthetic …, 2020 - ACS Publications
Clostridium cellulovorans DSM 743B can produce butyrate when grown on lignocellulose,
but it can hardly synthesize butanol. In a previous study, C. cellulovorans was successfully …

A systematically chromosomally engineered Escherichia coli efficiently produces butanol

H Dong, C Zhao, T Zhang, H Zhu, Z Lin, W Tao… - Metabolic …, 2017 - Elsevier
Biotechnological production of butanol in heterologous hosts has recently attracted many
interests. Of the heterologous hosts investigated to date, engineered Escherichia coli has …

Co‑cultivation of anaerobic fungi with Clostridium acetobutylicum bolsters butyrate and butanol production from cellulose and lignocellulose

JL Brown, MA Perisin, CL Swift… - Journal of Industrial …, 2022 - academic.oup.com
A system for co-cultivation of anaerobic fungi with anaerobic bacteria was established based
on lactate cross-feeding to produce butyrate and butanol from plant biomass. Several co …

Bioengineering advancements, innovations and challenges on green synthesis of 2, 5-furan dicarboxylic acid

RO Rajesh, TK Godan, R Sindhu, A Pandey… - …, 2020 - Taylor & Francis
The major drawback of chemical transformations for the production of 2, 5-furan dicarboxylic
acid (FDCA) implies the usage of hazardous chemicals, high temperature and high pressure …

A Targetron System for Gene Targeting in Thermophiles and Its Application in Clostridium thermocellum

G Mohr, W Hong, J Zhang, G Cui, Y Yang, Q Cui, Y Liu… - PloS one, 2013 - journals.plos.org
Background Targetrons are gene targeting vectors derived from mobile group II introns.
They consist of an autocatalytic intron RNA (a “ribozyme”) and an intron-encoded reverse …