Methoxyflurane is an inhaled analgesic administered via a disposable inhaler which has
been used in Australia for over 40 years for the management of pain associated with trauma …

Oligoanalgesia, the undertreatment of trauma-related pain using standard analgesics in
prehospital and emergency departments, has been extensively documented as one of the …

Introduction Inhaled low-dose methoxyflurane is approved in Europe for emergency relief of
moderate-to-severe trauma-related pain in adults, but data versus active comparators are …

The ongoing war in Ukraine presents unique challenges to prehospital medical care for
wounded combatants and civilians. The purpose of this article is to identify, describe, and …

Study objective The objective of the InMEDIATE study was to evaluate the change in
intensity of traumatic pain over the first 20 min in adult patients treated with methoxyflurane …

Background We aimed to investigate clinical benefits and economic costs of inhaled
methoxyflurane when used by ambulance staff for prehospital emergency patients with …

Aim: To systematically assess and rank the efficacy of opioid medications for traumatic pain
in the emergency department in terms of pain relief, adverse events and rescue analgesia …

Background Treatment of acute pain is an essential element of pre-hospital care for injured
and critically ill patients. Clinical studies indicate the need for improvement in the prehospital …

Purpose Opioid analgesics remain the cornerstone of treatment for severe trauma pain in
the emergency setting, but there are barriers to their use. This post hoc analysis of a …

Purpose Inadequate relief of pain is common in prehospital and hospital emergency
department (ED) settings. We investigated pain treatments and timelines in patients …