Objectives: The study was planned to determine cholinergic influence on different stages of
memory-acquisition, consolidation and recall in scopolamine-induced amnesia (memory …

The involvement of an impaired cholinergic neurotransmission in the pathophysiology of
cognitive impairment occurring in vascular dementia (VaD), as well as the possibility of …

Dehydroepiandrosterone (DHEA) is the most abundant steroid hormone in primates, which
is predominantly synthesized in the adrenal cortex. A characteristic curve of growth and …

Dementia is the most common psychiatric disorder in elderly patients, and Alzheimer's
disease1 (AD) is the most common cause. Much effort is devoted to elucidating the …

The role of the septohippocampal cholinergic system in memory disorders is well
established. The effects of cholinergic challenge in animals have been extensively studied …

Deep brain stimulation (DBS) has been found to have therapeutic effects in patients with
dementia, but DBS mechanisms remain elusive. To provide evidence for the effectiveness of …

Alzheimer's disease (AD) has few effective treatment options and continues to be a major
global health concern. AD is a neurodegenerative disease that typically affects elderly …

Individuals with Down's syndrome (DS) develop the pathological hallmarks of Alzheimer's
(AD) disease at an early age, subsequently followed by memory decline and dementia. We …

The interest in the action of nicotine in the central nervous system (CNS) has significantly
increased during the past 15 years. This is due in part to the growing importance of nicotine …

Among the diverse sets of nicotinic acetylcholine receptors (nAChRs), the α7 subtype is
highly expressed in the hippocampus and cortex and is thought to play important roles in a …