The α7 nicotinic acetylcholine receptor (nAChR) plays an important role in cognitive
processes and may represent a drug target for treating cognitive deficits in …

In the last years, an increasing interest has been paid to the olfactory system, particularly to
its abilities of plasticity and its potential continuous neurogenesis throughout adult life …

Olfactory dysfunction is a frequent and early feature of patients with neurodegenerative
disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD) and is very …

Recent studies suggest that estrogen replacement therapy can reduce the risk and severity
of Alzheimer's disease (AD)-related dementia in postmenopausal women. Many different …

This work describes for the first time signalon electrochemiluminescence (ECL) enzyme
biosensors based on cadmium sulfide nanocrystals (CdS NCs) formed in situ on the surface …

We have examined neuroanatomical, biochemical and endocrine parameters and spatial
learning in mice lacking the β2 subunit of the nicotinic acetylcholine receptor (nAChR) …

Although the hippocampus expresses nicotinic acetylcholine receptors (nAChRs) and
receives cholinergic innervation, the functional roles of these receptors are not completely …

Neuronal nicotinic receptors (nAChRs) are a heterogeneous family of ion channels
differently expressed in the nervous system where, by responding to the endogenous …

The overall aim of this article is to review current therapeutic strategies for treating AD, with a
focus on mitochondrially targeted antioxidant treatments. Recent advances in molecular …

The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections
are among the earliest pathological events in the pathogenesis of Alzheimer's disease (AD) …