[HTML][HTML] The importance of antimicrobial resistance in medical mycology

NAR Gow, C Johnson, J Berman, AT Coste… - Nature …, 2022 - nature.com
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance

P Koehler, M Bassetti, A Chakrabarti… - The Lancet Infectious …, 2021 - thelancet.com
Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway
epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary …

The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

[HTML][HTML] COVID-19 associated pulmonary aspergillosis (CAPA)—from immunology to treatment

A Arastehfar, A Carvalho, FL van de Veerdonk… - Journal of Fungi, 2020 - mdpi.com
Like severe influenza, coronavirus disease-19 (COVID-19) resulting in acute respiratory
distress syndrome (ARDS) has emerged as an important disease that predisposes patients …

[HTML][HTML] Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

PE Verweij, BJA Rijnders, RJM Brüggemann… - Intensive care …, 2020 - Springer
Purpose Invasive pulmonary aspergillosis is increasingly reported in patients with influenza
admitted to the intensive care unit (ICU). Classification of patients with influenza-associated …

CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models

M Seif, TK Kakoschke, F Ebel, MM Bellet… - Science Translational …, 2022 - science.org
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in
immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis …

[HTML][HTML] The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

[HTML][HTML] Fungicide effects on human fungal pathogens: cross-resistance to medical drugs and beyond

RW Bastos, L Rossato, GH Goldman… - PLoS Pathogens, 2021 - journals.plos.org
Fungal infections are underestimated threats that affect over 1 billion people, and Candida
spp., Cryptococcus spp., and Aspergillus spp. are the 3 most fatal fungi. The treatment of …

[HTML][HTML] The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda

PE Verweij, JA Lucas, MC Arendrup, P Bowyer… - Fungal Biology …, 2020 - Elsevier
Azole resistance is a concern for the management of diseases caused by Aspergillus
fumigatus in humans. Azole fungicide use in the environment has been identified as a …

[HTML][HTML] Azole-resistant COVID-19-associated pulmonary aspergillosis in an immunocompetent host: a case report

EFJ Meijer, ASM Dofferhoff, O Hoiting, JB Buil, JF Meis - Journal of Fungi, 2020 - mdpi.com
COVID-19-associated pulmonary aspergillosis (CAPA) is a recently described disease entity
affecting patients with severe pulmonary abnormalities treated in intensive care units …