Human Lung Organoids—A Novel Experimental and Precision Medicine Approach
L Kühl, P Graichen, N von Daacke, A Mende… - Cells, 2023 - mdpi.com
The global burden of respiratory diseases is very high and still on the rise, prompting the
need for accurate models for basic and translational research. Several model systems are …
need for accurate models for basic and translational research. Several model systems are …
[HTML][HTML] Human lung organoid: Models for respiratory biology and diseases
W Yang, Y Li, F Shi, H Liu - Developmental Biology, 2023 - Elsevier
The human respiratory system, consisting of the airway and alveoli, is one of the most
complex organs directly interfaced with the external environment. The diverse epithelial cells …
complex organs directly interfaced with the external environment. The diverse epithelial cells …
[HTML][HTML] Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 …
CT Ekanger, F Zhou, D Bohan, ML Lotsberg… - Frontiers in cellular …, 2022 - frontiersin.org
The ongoing coronavirus disease 2019 (COVID-19) pandemic has led to the initiation of
unprecedented research efforts to understand the pathogenesis mediated by Severe Acute …
unprecedented research efforts to understand the pathogenesis mediated by Severe Acute …
Novel opportunities from bioimaging to understand the trafficking and maturation of intracellular pulmonary surfactant and its role in lung diseases
Pulmonary surfactant (PS), a complex mixture of lipids and proteins, is essential for
maintaining proper lung function. It reduces surface tension in the alveoli, preventing …
maintaining proper lung function. It reduces surface tension in the alveoli, preventing …
Alveolar Organoids in Lung Disease Modeling
E Purev, K Bahmed, B Kosmider - Biomolecules, 2024 - mdpi.com
Lung organoids display a tissue-specific functional phenomenon and mimic the features of
the original organ. They can reflect the properties of the cells, such as morphology, polarity …
the original organ. They can reflect the properties of the cells, such as morphology, polarity …
[引用][C] High-throughput Droplet-engineered Organoid System for Small-tumors: Equipment and Applications
H Yang - 2023 - Tsinghua University