Depression in bipolar disorder (BD) patients presents major clinical challenges. As the
predominant psychopathology even in treated BD, depression is associated not only with …

Depressive syndromes are frequent and heterogeneous brain conditions with more than
90% of patients suffering from sleep complaints. Better characterizing this “sleep” domain …

Mood disorders are often characterised by alterations in circadian rhythms, sleep
disturbances and seasonal exacerbation. Conversely, chronobiological treatments utilise …

Although light therapy (LT) has been shown to be efficient in the treatment of seasonal and
non-seasonal depression, it is underused in clinical settings and antidepressant drugs (AD) …

Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

Objectives Bright light therapy (BLT) was reported as an effective adjunctive treatment option
for bipolar disorder. Previous meta‐analytic study showed that augmentation treatment with …

Sleep problems are highly prevalent in bipolar disorder (BD) and constitute an important
therapeutic focus in this population: They are highly impairing and distressing, are an area …

Background The combination of sleep deprivation and light therapy, called combined
chronotherapy, may yield positive short-and long-term results, even in patients with …

BackgroundBipolar disorder is a disabling disease characterized by the recurrence of mood
episodes. Successful strategies for the acute treatment of bipolar depression are still a …

Objective: This study aimed to examine the treatment-related changes of the fractional
amplitude of low-frequency fluctuations (fALFF) in the default mode network (DMN) across …