Nanomedicines are used to improve the efficacy and safety of pharmacotherapeutic
interventions. Unraveling the biological behavior of nanomedicines, including their …

Various types of nanoscale drug delivery systems (DDSs) have been developed for
therapeutic and/or diagnostic applications. However, most systems have been designed for …

Core-crosslinked polymeric micelles (CCPM) based on PEG-b-pHPMA-lactate are clinically
evaluated for the treatment of cancer. We macroscopically and microscopically investigated …

Core-cross-linked polymeric micelles (CCPMs) are a promising nanoparticle platform due to
favorable properties such as their long circulation and tumor disposition exploiting the …

For decades, there has been a growing interest in injectable subcutaneous formulations to
improve the absorption of drugs into the systemic circulation and to prolong their release …

The restrictive nature of the blood-brain barrier (BBB) prevents efficient treatment of many
brain diseases. Focused ultrasound in combination with microbubbles has shown to safely …

A sensitive, high-performance liquid chromatographic method was developed and validated,
for determination of docetaxel from docetaxel-entrapped core-crosslinked polymeric …

En este trabajo de fin de grado (TFG) se describen las principales nanopartículas
desarrolladas hasta el momento en terapia génica. Para su aplicación en esta terapia, las …