Fibroblasts are integral to the organization and function of all organs and play critical roles in
pathologies such as fibrosis; however, we have limited understanding of the fibroblasts that …

Chronic kidney disease (CKD) is characterized by persistent kidney dysfunction, ultimately
resulting in end-stage renal disease (ESRD). Renal fibrosis is a crucial pathological feature …

Managing renal fibrosis is challenging owing to the complex cell signaling redundancy in
diseased kidneys. Renal fibrosis involves an immune response dominated by macrophages …

Early diagnosis and treatment of renal fibrosis (RF) significantly affect the clinical outcomes
of chronic kidney diseases (CKDs). As the typical fibrotic ailment, RF is characterized by …

Wogonin, a vital bioactive compound extracted from the medicinal plant, Scutellaria
baicalensis, has been wildly used for its potential in mitigating the progression of chronic …

Recent publications raise the possibility that folic acid (FA), specifically unmetabolized folic
acid (UMFA), might promote the progression of organ fibrosis via signaling through folate …

Epithelial-to-mesenchymal transition (EMT) is crucial for the progression of renal
tubulointerstitial fibrosis, typically leading to end-stage renal failure. The role of Nuclear …

Background: Chronic Kidney Disease (CKD) impacts over 10% of the global population and
recently advancements in high-throughput analytical technologies are uncovering the …