[HTML][HTML] Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress
Y Shen, J Sun, X Sun - Journal of Nanobiotechnology, 2023 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …
[HTML][HTML] Therapeutic potential of cannabinoids in glaucoma
T Lindner, D Schmidl, L Peschorn, V Pai… - Pharmaceuticals, 2023 - mdpi.com
Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular
pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated …
pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated …
The latest drugs in development that reduce intraocular pressure in ocular hypertension and glaucoma
V Jayanetti, S Sandhu, JA Lusthaus - Journal of Experimental …, 2020 - Taylor & Francis
Glaucoma causes irreversible vision loss, with elevated intraocular pressure (IOP) being the
only known modifiable risk factor. There are a variety of medical and interventional options …
only known modifiable risk factor. There are a variety of medical and interventional options …
[HTML][HTML] Efficacy and safety of the travoprost intraocular implant in reducing topical IOP-lowering medication burden in patients with open-angle glaucoma or ocular …
Purpose A randomized, double-masked, multicenter, phase 2 trial to evaluate the long-term
safety and efficacy of travoprost intraocular implant, an extended-release drug delivery …
safety and efficacy of travoprost intraocular implant, an extended-release drug delivery …
Emerging drugs for the treatment of glaucoma: a review of phase II & III trials
TM Kaplan, AJ Sit - Expert Opinion on Emerging Drugs, 2022 - Taylor & Francis
Introduction Glaucoma is a progressive optic neuropathy and the leading cause of
irreversible vision loss. By 2040, the number of individuals with glaucoma is expected to …
irreversible vision loss. By 2040, the number of individuals with glaucoma is expected to …
Next generation therapeutics for retinal neurodegenerative diseases
MB Appell, J Pejavar, A Pasupathy… - Journal of Controlled …, 2024 - Elsevier
Neurodegenerative diseases affecting the visual system encompass glaucoma, macular
degeneration, retinopathies, and inherited genetic disorders such as retinitis pigmentosa …
degeneration, retinopathies, and inherited genetic disorders such as retinitis pigmentosa …
[HTML][HTML] Cannabidiol signaling in the eye and its potential as an ocular therapeutic agent
A Aebersold, M Duff, L Sloan… - Cellular physiology and …, 2021 - ncbi.nlm.nih.gov
Cannabidiol (CBD), the major non-intoxicating constituent of Cannabis sativa, has gained
recent attention due to its putative therapeutic uses for a wide variety of diseases. CBD was …
recent attention due to its putative therapeutic uses for a wide variety of diseases. CBD was …
[HTML][HTML] The effects of cannabidiol on aqueous humor outflow and trabecular meshwork cell signaling
AS Aebersold, ZH Song - Cells, 2022 - mdpi.com
Intraocular pressure (IOP) is regulated primarily through aqueous humor production by
ciliary body and drainage through uveoscleral and trabecular meshwork (TM) tissues. The …
ciliary body and drainage through uveoscleral and trabecular meshwork (TM) tissues. The …
Suprachoroidal injection of polyzwitterion hydrogel for treating glaucoma
H Hao, B He, B Yu, J Yang, X Xing, W Liu - Biomaterials Advances, 2022 - Elsevier
Glaucoma is the primary cause of irreversible blindness worldwide. The current treatments
are primarily based on drug usage or surgical operation to reduce intraocular pressure …
are primarily based on drug usage or surgical operation to reduce intraocular pressure …
Impact of glaucoma medications on subsequent Schlemm's canal surgery outcome: Cox proportional hazard model and propensity score‐matched analysis
M Okuda‐Arai, S Mori, F Takano, K Ueda… - Acta …, 2024 - Wiley Online Library
Purpose The impact of various preoperative glaucoma medications on Schlemm's canal
surgery outcomes remains unclear. This study aimed to investigate the impact of …
surgery outcomes remains unclear. This study aimed to investigate the impact of …