Background Coronaviruses mainly affect the respiratory system; however, there are reports
of SARS-CoV and MERS-CoV causing neurological manifestations. We aimed at discussing …

Background The signs and symptoms of Zika virus infection are usually mild and self-limited.
However, the disease has been linked to neurological complications such as Guillain-Barré …

At the time of this writing, healthcare systems are facing worldwide the pandemic of the
coronavirus severe acute respiratory coronavirus 2 (SARS-COV-2) and its associated …

Context.—The number of neonates with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is increasing, and in a few there are reports of intrauterine infection …

Brazil is experiencing among the world's fastest demographic aging worldwide. This
demographic transition is occurring in a context of few resources and great social …

Objetivo: Analisar as taxas de mortalidade e as principais causas de morte na infância no
Brasil e estados, entre 1990 e 2015, utilizando estimativas do estudo Carga Global de …

Summary Background The Zika virus epidemic and associated congenital infections have
prompted rapid vaccine development. We assessed two new DNA vaccines expressing …

Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus
nonstructural protein 1 (NS1) is a secreted glycoprotein involved in viral replication, immune …

Zika Virus (ZIKV) is a Flavivirus transmitted primarily via the bite of infected Aedes aegypti
mosquitoes. Globally, 87 countries and territories have recorded autochthonous mosquito …

The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …