Novel genetic causes of pituitary adenomas

F Caimari, M Korbonits - Clinical Cancer Research, 2016 - AACR
Recently, a number of novel genetic alterations have been identified that predispose
individuals to pituitary adenomas. Clinically relevant pituitary adenomas are relatively …

Genetic and epigenetic causes of pituitary adenomas

M Chang, C Yang, X Bao, R Wang - Frontiers in endocrinology, 2021 - frontiersin.org
Pituitary adenomas (PAs) can be classified as non-secreting adenomas, somatotroph
adenomas, corticotroph adenomas, lactotroph adenomas, and thyrotroph adenomas …

Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects

S Pepe, M Korbonits, D Iacovazzo - Journal of Endocrinology, 2019 - joe.bioscientifica.com
While 95% of pituitary adenomas arise sporadically without a known inheritable
predisposing mutation, in about 5% of the cases they can arise in a familial setting, either …

Anti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis

MJ Egidi, S Krug, J Haybaeck, P Michl… - British Journal of …, 2023 - nature.com
Abstract Background Pancreatic neuroendocrine tumors (PNETs) represent a distinct
hypervascularized tumor entity, often diagnosed at metastatic stage. Therapeutic efficacy of …

Pheochromocytoma: the first metabolic endocrine cancer

I Jochmanova, K Pacak - Clinical cancer research, 2016 - AACR
Dysregulated metabolism is one of the key characteristics of cancer cells. The most
prominent alterations are present during regulation of cell respiration, which leads to a …

Pancreatic neuroendocrine tumors

J Sun - Intractable & rare diseases research, 2017 - jstage.jst.go.jp
Pancreatic neuroendocrine neoplasms (pNENs) are a heterogeneous group of tumors
including well differentiated pancreatic neuroendocrine tumors (pNETs) and …

Improving quality of life in patients with pancreatic neuroendocrine tumor following peptide receptor radionuclide therapy assessed by EORTC QLQ-C30

M Marinova, M Mücke, L Mahlberg, M Essler… - European journal of …, 2018 - Springer
Abstract Introduction Neuroendocrine tumors (NETs) have proven to be appropriate
neoplasms for peptide receptor radionuclide therapy (PRRT), as the majority of these slow …

The landmark series: management of small bowel neuroendocrine tumors

CG Tran, SK Sherman, JR Howe - Annals of surgical oncology, 2021 - Springer
Surgical resection is the foundation for treatment of small bowel neuroendocrine tumors
(SBNETs). Guidelines for surgical management of SBNETs rely on retrospective data, which …

Small bowel neuroendocrine tumors

CG Tran, SK Sherman, JR Howe - Current problems in surgery, 2020 - Elsevier
Neuroendocrine tumors (NETs) are a heterogeneous group of malignancies arising from
neural crest-derived cells throughout the body. The presentation and natural history of NETs …

Neoadjuvant therapy in pancreatic neuroendocrine neoplasms: A systematic review and meta-analysis

Y Li, Z Fan, F Zhang, J Yang, M Shi, S Liu… - Frontiers in …, 2022 - frontiersin.org
Background and Objectives Neoadjuvant therapy plays an increasingly important role in
pancreatic neuroendocrine neoplasms (pNENs), but the systematic evaluation of its efficacy …