Severe traumatic brain injury: targeted management in the intensive care unit

N Stocchetti, M Carbonara, G Citerio, A Ercole… - The Lancet …, 2017 - thelancet.com
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

Paroxysmal sympathetic hyperactivity: the storm after acute brain injury

G Meyfroidt, IJ Baguley, DK Menon - The Lancet Neurology, 2017 - thelancet.com
A substantial minority of patients who survive an acquired brain injury develop a state of
sympathetic hyperactivity that can persist for weeks or months, consisting of periodic …

Proceedings of the first curing coma campaign NIH symposium: challenging the future of research for coma and disorders of consciousness

J Claassen, Y Akbari, S Alexander, MK Bader, K Bell… - Neurocritical care, 2021 - Springer
Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Identification and management of paroxysmal sympathetic hyperactivity after traumatic brain injury

RZ Zheng, ZQ Lei, RZ Yang, GH Huang… - Frontiers in …, 2020 - frontiersin.org
Paroxysmal sympathetic hyperactivity (PSH) has predominantly been described after
traumatic brain injury (TBI), which is associated with hyperthermia, hypertension …

Decreased levels of hydrogen sulfide in the hypothalamic paraventricular nucleus contribute to sympathetic hyperactivity induced by cerebral infarction

J Sun, Y Miao, P Wang, Q Guo, D Tian, H Xue… - Hypertension …, 2024 - nature.com
Paroxysmal sympathetic hyperactivity (PSH) is a common clinical feature secondary to
ischemic stroke (IS), but its mechanism is poorly understood. We aimed to investigate the …

Paroxysmal sympathetic hyperactivity

RA Scott, AA Rabinstein - Seminars in neurology, 2020 - thieme-connect.com
Paroxysmal sympathetic hyperactivity (PSH) is a relatively common, but often unrecognized,
complication of acute diffuse or multifocal brain diseases, most frequently encountered in …

Predicting outcome of acquired brain injury by the evolution of paroxysmal sympathetic hyperactivity signs

LF Lucca, A De Tanti, F Cava, A Romoli… - Journal of …, 2021 - liebertpub.com
In this multi-center study, we provide a systematic evaluation of the clinical variability
associated with paroxysmal sympathetic hyperactivity (PSH) in patients with acquired brain …

Leveraging continuous vital sign measurements for real-time assessment of autonomic nervous system dysfunction after brain injury: a narrative review of current and …

J Podell, M Pergakis, S Yang, R Felix, G Parikh… - Neurocritical Care, 2022 - Springer
Subtle and profound changes in autonomic nervous system (ANS) function affecting
sympathetic and parasympathetic homeostasis occur as a result of critical illness. Changes …

The use of the PSH-AM in patients with diffuse axonal injury and autonomic dysregulation: a cohort study and review

MM van Eijck, MOP Sprengers, AW Oldenbeuving… - Journal of Critical …, 2019 - Elsevier
Purpose 1) To determine the clinical expression and consequences of autonomic
dysregulation in patients with diffuse axonal injury (DAI), and 2) to study the use of the …

Paroxysmal sympathetic hyperactivity rate in vegetative or minimally conscious state after acquired brain injury evaluated by paroxysmal sympathetic hyperactivity …

LF Lucca, L Pignolo, E Leto, M Ursino… - Journal of …, 2019 - liebertpub.com
The rate of paroxysmal sympathetic hyperactivity (PSH) was retrospectively assessed using
the Paroxysmal Sympathetic Hyperactivity–Assessment Measure (PSH-AM) scale in patients …