Current understanding of the molecular and cellular pathology of diabetic retinopathy

DA Antonetti, PS Silva, AW Stitt - Nature Reviews Endocrinology, 2021 - nature.com
Diabetes mellitus has profound effects on multiple organ systems; however, the loss of
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …

Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)

I Lains, JC Wang, Y Cui, R Katz, F Vingopoulos… - Progress in retinal and …, 2021 - Elsevier
The advent of optical coherence tomography (OCT) revolutionized both clinical assessment
and research of vitreoretinal conditions. Since then, extraordinary advances have been …

Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities

PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …

[HTML][HTML] Artificial intelligence in retina

U Schmidt-Erfurth, A Sadeghipour, BS Gerendas… - Progress in retinal and …, 2018 - Elsevier
Major advances in diagnostic technologies are offering unprecedented insight into the
condition of the retina and beyond ocular disease. Digital images providing millions of …

Deep learning in ophthalmology: the technical and clinical considerations

DSW Ting, L Peng, AV Varadarajan, PA Keane… - Progress in retinal and …, 2019 - Elsevier
The advent of computer graphic processing units, improvement in mathematical models and
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …

[HTML][HTML] Towards standardizing retinal optical coherence tomography angiography: a review

DM Sampson, AM Dubis, FK Chen… - Light: science & …, 2022 - nature.com
The visualization and assessment of retinal microvasculature are important in the study,
diagnosis, monitoring, and guidance of treatment of ocular and systemic diseases. With the …

[HTML][HTML] Neurodegeneration in diabetic retinopathy: does it really matter?

R Simó, AW Stitt, TW Gardner - Diabetologia, 2018 - Springer
The concept of diabetic retinopathy as a microvascular disease has evolved, in that it is now
considered a more complex diabetic complication in which neurodegeneration plays a …

Automatic interpretation and clinical evaluation for fundus fluorescein angiography images of diabetic retinopathy patients by deep learning

Z Gao, X Pan, J Shao, X Jiang, Z Su, K Jin… - British Journal of …, 2023 - bjo.bmj.com
Background/aims Fundus fluorescein angiography (FFA) is an important technique to
evaluate diabetic retinopathy (DR) and other retinal diseases. The interpretation of FFA …

Optical coherence tomography angiography in diabetic retinopathy: an updated review

Z Sun, D Yang, Z Tang, DS Ng, CY Cheung - Eye, 2021 - nature.com
Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus.
Optical coherence tomography angiography (OCTA) has been developed to visualize the …

Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …