Genotype frequencies of CYP2C19, P2Y12 and GPIIIa polymorphisms in coronary heart disease patients of Han ethnicity, and their impact on clopidogrel …
W Ou, Y He, A Li, B Liu, L Jin - International heart journal, 2016 - jstage.jst.go.jp
To investigate the genotype frequencies of cytochrome P450, family2, subfamily C,
polypeptide19 (CYP2C19); P2Y12 receptor; and glycoprotein IIIa polymorphisms in patients …
polypeptide19 (CYP2C19); P2Y12 receptor; and glycoprotein IIIa polymorphisms in patients …
P-glycoprotein polymorphism C3435T is associated with dose-adjusted clopidogrel and 2-oxo-clopidogrel concentration
D Stokanovic, VN Nikolic, SS Konstantinovic… - Pharmacology, 2016 - karger.com
Abstract Background/Aims: One of the most common polymorphisms of ABCB1 gene, a
synonymous mutation C3435T (rs1045642), is associated with increased in vivo activity. The …
synonymous mutation C3435T (rs1045642), is associated with increased in vivo activity. The …
Effects of Danshen capsules on the pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers
C Zhou, M Xu, H Yu, XT Zheng, ZF Zhong… - Food and Chemical …, 2018 - Elsevier
Nowadays, the Herb-drug combination is becoming increasingly popular in China. However,
the possible interaction induced by their combination was examined rarely. The aim of this …
the possible interaction induced by their combination was examined rarely. The aim of this …
Distribution of CYP2C19, ABCB1 and PON1 polymorphisms in Chinese Han, Hui, Uygur and Kazak patients with coronary atherosclerotic heart disease
L Ma, Y Yuan, J Li, C Yu, J Zhao - International Journal of …, 2020 - Wiley Online Library
Summary CYP2C19, ABCB1 and PON1 polymorphisms involve in the metabolism and
absorption of clopidogrel, which may be associated with interethnic variability of clopidogrel …
absorption of clopidogrel, which may be associated with interethnic variability of clopidogrel …
CRISPLD1 rs12115090 polymorphisms alters antiplatelet potency of clopidogrel in coronary artery disease patients in Chinese Han
JY Wang, YJ Zhang, H Li, XL Hu, MP Li, PY Song… - Gene, 2018 - Elsevier
Background Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is a
recommended treatment for coronary artery disease (CAD) patients undergoing …
recommended treatment for coronary artery disease (CAD) patients undergoing …
Association of KDR rs1870377 genotype with clopidogrel resistance in patients with post percutaneous coronary intervention
Background Clopidogrel is an antiplatelet therapy that is widely used in pre and post
percutaneous (PCI) coronary intervention procedures to prevent platelet aggregation and …
percutaneous (PCI) coronary intervention procedures to prevent platelet aggregation and …
Expression of ATP-binding cassette subfamily B member 1 gene in peripheral blood of patients with acute myocardial infarction
J Ruan, H Meng, Y Chen, Z Yan, X Li, F Meng - Bioengineered, 2022 - Taylor & Francis
This study aimed to determine the amount of expression of the ATP-binding cassette
subfamily B member 1 (ABCB1) gene chip as a prospective diagnostic marker for acute …
subfamily B member 1 (ABCB1) gene chip as a prospective diagnostic marker for acute …
Pharmacogenetic testing by polymorphic markers 681G>A and 636G>A CYP2C19 gene in patients with acute coronary syndrome and gastric ulcer in the Republic of …
DS Fedorinov, KB Mirzaev, DV Ivashchenko… - Drug Metabolism and …, 2018 - degruyter.com
Background: The focus of the study is to determine the prevalence of CYP2C19 alleles,
associated with the risk of changes in the pharmacological response to clopidogrel and …
associated with the risk of changes in the pharmacological response to clopidogrel and …
Effects of CYP2C19 genetic polymorphisms on the pharmacokinetic and pharmacodynamic properties of clopidogrel and its active metabolite in healthy Chinese …
BL Song, M Wan, D Tang, C Sun, YB Zhu, N Linda… - Clinical Therapeutics, 2018 - Elsevier
Purpose Some studies in the white population have shown that carriers of at least 1 loss-of-
function allele in the gene that encodes the cytochrome P-450 2C19 isozyme (CYP2C19) …
function allele in the gene that encodes the cytochrome P-450 2C19 isozyme (CYP2C19) …
Фармакогенетика антитромботических препаратов: современное состояние проблемы
ЕС Кропачева - Атеротромбоз, 2018 - cyberleninka.ru
В обзоре отражены основные исследования, посвященные изучению генетических
мишеней индивидуальной вариабельности лекарственного ответа на …
мишеней индивидуальной вариабельности лекарственного ответа на …