[HTML][HTML] Sheep and goat genome engineering: from random transgenesis to the CRISPR era

P Kalds, S Zhou, B Cai, J Liu, Y Wang… - Frontiers in …, 2019 - frontiersin.org
Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …

When Less Is More: Targeting the Myostatin Gene in Livestock for Augmenting Meat Production

P Kalds, S Zhou, S Huang, Y Gao… - Journal of Agricultural …, 2023 - ACS Publications
How to increase meat production is one of the main questions in animal breeding. Selection
for improved body weight has been made and, due to recent genomic advances, naturally …

[HTML][HTML] Interaction of fibromodulin and myostatin to regulate skeletal muscle aging: an opposite regulation in muscle aging, diabetes, and intracellular lipid …

EJ Lee, SS Ahmad, JH Lim, K Ahmad, S Shaikh… - Cells, 2021 - mdpi.com
The objective of this study was to investigate fibromodulin (FMOD) and myostatin (MSTN)
gene expressions during skeletal muscle aging and to understand their involvements in this …

[HTML][HTML] MSTN mutant promotes myogenic differentiation by increasing demethylase TET1 expression via the SMAD2/SMAD3 pathway

L Gao, M Yang, Z Wei, M Gu, L Yang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Myostatin (MSTN) is mostly expressed in skeletal muscle and plays crucial roles in the
negative regulation of muscle mass development. The methylation and demethylation of …

Identification and expression characterization of the myostatin (MSTN) gene and association analysis with growth traits in the razor clam Sinonovacula constricta

D Niu, L Wang, Z Bai, S Xie, H Zhao, J Li - Gene, 2015 - Elsevier
Myostatin (MSTN) is a member of the transforming growth factor-β superfamily (TGF-β) and
is an important negative regulator of muscle growth in vertebrates. In this study, we cloned …

[HTML][HTML] Expression of MSTN gene and its correlation with pectoralis muscle fiber traits in the domestic pigeons (Columba livia)

HH Liu, HG Mao, XY Dong, HY Cao, K Liu, ZZ Yin - Poultry science, 2019 - Elsevier
Myostatin (MSTN) is a negative regulator of skeletal muscle growth and plays an important
role in muscle development. In this research, we constructed a tissue expression profile of …

[HTML][HTML] Livestock cell types with myogenic differentiation potential: considerations for the development of cultured meat

M Olenic, C Deelkens, E Heyman, E De Vlieghere… - animal, 2024 - Elsevier
With the current environmental impact of large-scale animal production and societal
concerns about welfare of farm animals, researchers are questioning whether we can …

Expression of 2A peptide mediated tri-fluorescent protein genes were regulated by epigenetics in transgenic sheep

Y Tian, W Li, L Wang, C Liu, J Lin, X Zhang… - Biochemical and …, 2013 - Elsevier
A number of gene therapy applications and basic research would benefit from vectors
expressing multiple genes. In this study, we constructed 2A peptide based tricistronic …

bta-miR-29b attenuates apoptosis by directly targeting caspase-7 and NAIF1 and suppresses bovine viral diarrhea virus replication in MDBK cells

Q Fu, H Shi, M Shi, L Meng, H Zhang… - Canadian journal of …, 2014 - cdnsciencepub.com
MicroRNAs (miRNAs) are small, endogenous, noncoding RNA molecules that serve as
powerful regulators of multiple cellular processes, including apoptosis, differentiation …

[PDF][PDF] Molecular analysis of ovine myostatin gene (MSTN) in northeast Bulgarian merino sheep breed using PCR-RFLP

I Dimitrova, M Bozhilova-Sakova… - Bulgarian Journal of …, 2016 - academia.edu
Abstract DIMITROVA, I., M. BOZHILOVA-SAKOVA, N. STANCHEVA and T. TZONEV, 2016.
Molecular analysis of ovine myostatin gene (MSTN) in Northeast Bulgarian Merino Sheep B …