Tendon pain remains an enigma. Many clinical features are consistent with tissue disruption—
the pain is localised, persistent and specifically associated with tendon loading, whereas …

[Frontiers in Bioscience 14, 5291-5338, June 1, 2009] 5291 Neurobiology of depression,
fibromyalgia and neuropathic pain Vladimi Page 1 [Frontiers in Bioscience 14, 5291-5338, June …

Background Activated astrocytes play important roles in chronic post-surgical pain (CPSP).
Recent studies have shown reactive astrocytes are classified into A1 and A2 phenotypes …

Chronic alcohol consumption produces painful peripheral neuropathy for which there is no
reliable successful therapy, mainly due to lack of understanding of its pathobiology …

Glial activation participates in the mediation of pain including neuropathic pain, due to
release of neuroexcitatory, proinflammatory products. Glial activation is now known to occur …

In the spinal cord, neuron and glial cells actively interact and contribute to neurofunction.
Surprisingly, both cell types have similar receptors, transporters and ion channels and also …

Introduction Neuropathic pain is a debilitating condition. The importance of neuroimmune
interactions in neuropathic pain has been evidenced by the involvement of different immune …

Doxycycline is used to treat infective diseases because of its broadspectrum efficacy. High
dose administration (100 or 200 mg/day) is often responsible for development of bacterial …

Spinal cord injury induces maladaptive synaptic transmission in the somatosensory system
that results in chronic central neuropathic pain. Recent literature suggests that glial-neuronal …

There is a paucity of data on the role of microglia and neuroinflammatory processes in the
association between chronic pain and depression. The current study examined the effect of …