Immunoglobulin (IG) replacement therapy has served as lifesaving treatment in primary
immunodeficiency diseases (PID) for more than six decades. Approximately 70% of patients …

Background. Efforts have been made worldwide to improve awareness and treatment of
primary immunodeficiency (PID). This has also gained momentum on the African continent …

Background Primary antibody deficiency (PAD) is the most common group of primary
immunodeficiency disorders (PID), with a broad spectrum of clinical features ranging from …

Objectives: Impairment in early B-cell development can cause a predominantly antibody
deficiency with severe depletion of peripheral B-cells. Mutations in the gene encoding for …

Las inmunodeficiencias primarias son un grupo heterogéneo de trastornos hereditarios
ocasionados por defectos del desarrollo o función del sistema inmunológico, la mayoría se …

Background: Ataxia telangiectasia (AT) is a primary immunodeficiency associated with
recurrent infections. We aimed to investigate clinical and immunological classification in AT …

Objectives: In the context of the unknown economic burden imposed by primary
immunodeficiency diseases, in this study, we sought to calculate the costs associated with …

Background: Primary immunodeficiency diseases are a group of disorders that result from a
variety of defects of the immune system. Primary antibody deficiencies (PADs) are the most …

Introduction The prevalence of undiagnosed primary immunodeficiency diseases is
remarkably high and contributes to increasing the rate of morbidity and mortality among this …

Background We aimed to establish the prevalence of parental consanguinity among patients
with primary immunodeficiency diseases (PID) and compare the prevalence with the general …