Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

B Lin, P Xu, J Zheng, X Deng, Q Ye, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …

A comprehensive metabolomics and lipidomics atlas for the legumes common bean, chickpea, lentil and lupin

M Bulut, R Wendenburg, E Bitocchi, E Bellucci… - The Plant …, 2023 - Wiley Online Library
Legumes represent an important component of human and livestock diets; they are rich in
macro‐and micronutrients such as proteins, dietary fibers and polyunsaturated fatty acids …

Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria …

H Liao, H Quan, B Huang, H Ji, T Zhang, J Chen… - Phytochemistry, 2023 - Elsevier
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a
Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Phytochemicals against anti‐diabetic complications: targeting the advanced glycation end product signaling pathway

A Parveen, R Sultana, SM Lee, TH Kim… - Archives of Pharmacal …, 2021 - Springer
The role of advanced glycation end products (AGEs) is not limited to diabetes and diabetes-
related complications. There are multiple modulators, including the receptor for advanced …

The biological activities of quinolizidine alkaloids

J Zhang, YQ Liu, J Fang - The Alkaloids: Chemistry and Biology, 2023 - Elsevier
Quinolizidine alkaloids isolated from various marine and terrestrial animals and plants are
primarily composed of lupinine-, matrine-, and sparteine-type alkaloids. Matrine …

Phytotoxic Activity of Alkaloids in the Desert Plant Sophora alopecuroides

L Lei, Y Zhao, K Shi, Y Liu, Y Hu, H Shao - Toxins, 2021 - mdpi.com
Sophora alopecuroides is known to produce relatively large amounts of alkaloids; however,
their ecological consequences remain unclear. In this study, we evaluated the allelopathic …

Alopecines A–E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides

XF Wang, Z Zhu, TT Hao, QQ Fang, K Jiang, SJ Qu… - Bioorganic …, 2020 - Elsevier
Abstract Alopecines A–E (1–5), five unusual matrine-type alkaloids featuring with an
additional dichlorocyclopropane (1–3) or a di/tri-chloromethyl (4/5) attached on the D ring …

Comprehensive investigation of the content and the origin of matrine-type alkaloids in Chinese honeys

Z Wang, T Zu, X Huang, X Jiang, G Jia, J Xu, Z Cui… - Food Chemistry, 2023 - Elsevier
Abstract A HPLC-MS/MS method for simultaneous determination of four matrine-type
alkaloids (matrine, oxymatrine, sophocarpine and sophoridine) in honey was established …