Infections at the maternal–fetal interface: an overview of pathogenesis and defence
CJ Megli, CB Coyne - Nature Reviews Microbiology, 2022 - nature.com
Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …
Maternal immunological adaptation during normal pregnancy
B Abu-Raya, C Michalski, M Sadarangani… - Frontiers in …, 2020 - frontiersin.org
The risk and severity of specific infections are increased during pregnancy due to a
combination of physiological and immunological changes. Characterizing the maternal …
combination of physiological and immunological changes. Characterizing the maternal …
Early prediction of preeclampsia in pregnancy with cell-free RNA
MN Moufarrej, SK Vorperian, RJ Wong, AA Campos… - Nature, 2022 - nature.com
Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study
the development of pregnancy-related complications in a non-invasive manner and to …
the development of pregnancy-related complications in a non-invasive manner and to …
Shared and distinct functions of type I and type III interferons
HM Lazear, JW Schoggins, MS Diamond - Immunity, 2019 - cell.com
Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …
including induction by viral infection, activation of shared signaling pathways, and …
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?
R Pique-Regi, R Romero, AL Tarca, F Luca, Y Xu… - Elife, 2020 - elifesciences.org
The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million …
Chronic histiocytic intervillositis with trophoblast necrosis is a risk factor associated with placental infection from coronavirus disease 2019 (COVID-19) and intrauterine …
DA Schwartz, M Baldewijns… - … of pathology & …, 2021 - meridian.allenpress.com
Context.—The number of neonates with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is increasing, and in a few there are reports of intrauterine infection …
(SARS-CoV-2) infection is increasing, and in a few there are reports of intrauterine infection …
The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease
MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …
PLA2G6 guards placental trophoblasts against ferroptotic injury
O Beharier, VA Tyurin, JP Goff… - Proceedings of the …, 2020 - National Acad Sciences
The recently identified ferroptotic cell death is characterized by excessive accumulation of
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes
N Chaudhary, AN Newby, ML Arral… - Proceedings of the …, 2024 - National Acad Sciences
Treating pregnancy-related disorders is exceptionally challenging because the threat of
maternal and/or fetal toxicity discourages the use of existing medications and hinders new …
maternal and/or fetal toxicity discourages the use of existing medications and hinders new …
COVID‐19 in pregnancy: Placental and neonatal involvement
E Prochaska, M Jang, I Burd - American journal of reproductive …, 2020 - Wiley Online Library
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has caused over 12 million infections and more than 550 000 deaths. 1 Morbidity and …
has caused over 12 million infections and more than 550 000 deaths. 1 Morbidity and …