Early pregnancy is a complex and well-orchestrated differentiation process that involves all
the cellular elements of the fetal-maternal interface. Aberrant trophoblast-decidual …

Zika virus (ZIKV) and dengue virus (DENV) are genetically and antigenically related
flaviviruses that now co-circulate in much of the tropical and subtropical world. The rapid …

Many studies have focused on psychoimmunological mechanisms of risk for stress-related
mental health disorders. However, significantly fewer studies have focused on …

Recurrent pregnancy loss (RPL) has become an important reproductive health issue
worldwide. RPL affects about 2%–3% of reproductive-aged women, and makes serious …

Among the most worrisome consequences of a newly emergent viral disease is its potential
effect on pregnant women. It is particularly important to determine whether a novel virus is …

Insufficient extravillous trophoblast (EVT) invasion during early placentation has been
shown to contribute to recurrent pregnancy loss (RPL). However, the regulatory factors …

Since the explosive outbreak of Zika virus in Brazil and South/Central America in 2015–
2016, the frequency of infections has subsided, but Zika virus remains present in this region …

Recurrent spontaneous abortion (RSA) has various causes, including chromosomal
abnormalities, a prethrombotic state, and abnormal uterine anatomical factors. However, in …

The placenta represents the maternal-fetal vascular interface. It is capable of supplying the
bioenergetic needs of the developing conceptus. It is composed of different cell types that …

The placental barrier plays a key role in protecting the developing fetus from xenobiotics and
exchanging substances between the fetus and mother. However, the trophoblast cell lines …