Staging of prostate cancer

L Cheng, R Montironi, DG Bostwick… - …, 2012 - Wiley Online Library
Cheng L, Montironi R, Bostwick DG, Lopez‐Beltran A & Berney DM (2012) Histopathology
60, 87–117 Staging of prostate cancer Prostatic carcinoma (PCa) is a significant cause of …

Management of patients with node-positive prostate cancer at radical prostatectomy and pelvic lymph node dissection: a systematic review

G Marra, M Valerio, I Heidegger, I Tsaur… - European urology …, 2020 - Elsevier
Context Optimal management of prostate cancer (PCa) patients with lymph node invasion at
radical prostatectomy and pelvic lymph node dissection still remains unclear. Objective To …

Prostate-specific membrane antigen expression as a predictor of prostate cancer progression

S Perner, MD Hofer, R Kim, RB Shah, H Li, P Möller… - Human pathology, 2007 - Elsevier
Distinguishing aggressive prostate cancer from indolent disease represents an important
clinical challenge, because current therapy may lead to overtreatment of men with limited …

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease

D Di Vizio, J Kim, MH Hager, M Morello, W Yang… - Cancer research, 2009 - AACR
Oncosomes have recently been described as membrane-derived microvesicles secreted by
cancer cells, which transfer oncogenic signals and protein complexes across cell …

TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

S Perner, F Demichelis, R Beroukhim, FH Schmidt… - Cancer research, 2006 - AACR
Prostate cancer is a common and clinically heterogeneous disease with marked variability in
progression. The recent identification of gene fusions of the 5′-untranslated region of …

TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion

S Perner, JM Mosquera, F Demichelis… - The American journal …, 2007 - journals.lww.com
Prostate cancer (PCA) is one of the most prevalent cancers and a major leading cause of
morbidity and mortality in the Western world. The TMPRSS2-ERG fusion was recently …

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

MP Steinkamp, OA O'Mahony, M Brogley, H Rehman… - Cancer research, 2009 - AACR
Mutations in the androgen receptor (AR) that enable activation by antiandrogens occur in
hormone-refractory prostate cancer, suggesting that mutant ARs are selected by treatment …

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model

KD Mertz, SR Setlur, SM Dhanasekaran, F Demichelis… - Neoplasia, 2007 - Elsevier
Recent studies have established that a significant fraction of prostate cancers harbor a
signature gene fusion between the 5'region of androgen-regulated TMPRSS2 and an ETS …

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

KM Gust, MD Hofer, SR Perner, R Kim, AM Chinnaiyan… - Neoplasia, 2009 - Elsevier
Localized prostate cancer (CaP) can be cured using several strategies. However, the need
to identify active substances in advanced tumor stages is tremendous, as the outcome in …

The prognostic value of lymph node staging with prostate‐specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) and …

D Meijer, RH Ettema, PJ van Leeuwen… - BJU …, 2023 - Wiley Online Library
Objectives To investigate whether patients with suspected pelvic lymph node metastases
(molecular imaging [mi] N1) on staging prostate‐specific membrane antigen (PSMA) …