[HTML][HTML] Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023 - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

A two-pronged detection of atherosclerosis with a dual-channel fluorescent probe for viscosity and hypochlorous acid

Z Wang, S Wang, B Wang, J Shen, L Zhao, F Yu… - Chemical Engineering …, 2023 - Elsevier
The precise detection of atherosclerosis has been a research hot point since its importance
in the diagnosis of cardiovascular diseases. Here we synthesized a near-infrared …

[HTML][HTML] Inflammation, oxidative stress, senescence in atherosclerosis: thioredoxine-1 as an emerging therapeutic target

K El Hadri, R Smith, E Duplus, C El Amri - International journal of …, 2021 - mdpi.com
Atherosclerosis is a leading cause of cardiovascular diseases (CVD) worldwide and
intimately linked to aging. This pathology is characterized by chronic inflammation, oxidative …

Targeting adipokines in polycystic ovary syndrome and related metabolic disorders: from experimental insights to clinical studies

Y Xu, H Zhu, W Li, D Chen, Y Xu, A Xu, D Ye - Pharmacology & …, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) affects approximately 15% of women of reproductive age
worldwide. It is the most prevalent endocrine disorder with marked risks for female infertility …

[HTML][HTML] Th17 cells and IL-17A in ischemic stroke

J Wang, Y Gao, Y Yuan, H Wang, Z Wang… - Molecular …, 2024 - Springer
The neurological injury and repair mechanisms after ischemic stroke are complex. The
inflammatory response is present throughout stroke onset and functional recovery, in which …

Cardioprotective effects of Amentoflavone by suppression of apoptosis and inflammation on an in vitro and vivo model of myocardial ischemia-reperfusion injury

W Li, D Li, Y Qin, C Sun, Y Wang, L Gao… - International …, 2021 - Elsevier
Inflammation modulation is currently considered a promising therapeutic strategy to
counteract the burden of cardiovascular disease. Amentoflavone (AME) is a natural …

[HTML][HTML] VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys

MM Vroom, H Lu, M Lewis, BA Thibodeaux… - Journal of Lipid …, 2024 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of disease
burden in the world and is highly correlated with chronic elevations of LDL-C. LDL-C …

[HTML][HTML] CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study

N Cai, C Li, X Gu, W Zeng, J Zhong, J Liu… - BMC Cardiovascular …, 2023 - Springer
Background Genetic factors have a certain proportion in the risk factors of hypertension. The
purpose was to investigate the relationship of cytochrome P450 2C19 (CYP2C19) …

Fatal attractions that trigger inflammation and drive atherosclerotic disease

H Sharma, K Mossman… - European Journal of …, 2024 - Wiley Online Library
Background Atherosclerosis is the salient, underlying cause of cardiovascular diseases,
such as arrhythmia, coronary artery disease, cardiomyopathy, pulmonary embolism and …