[HTML][HTML] Translational and clinical significance of DAMPs, PAMPs, and PRRs in trauma-induced inflammation

V Rai, G Mathews, DK Agrawal - Archives of clinical and …, 2022 - ncbi.nlm.nih.gov
Increased morbidity and mortality after polytrauma due to multiple organ failure (MOF) is a
major concern for clinicians. Systemic inflammatory response syndrome (SIRS) and sepsis …

[HTML][HTML] Review on the role of salivary biomarkers in the diagnosis of mild traumatic brain injury and post-concussion syndrome

I Mavroudis, F Petridis, IM Balmus, A Ciobica… - Diagnostics, 2023 - mdpi.com
(1) Background: While mild traumatic brain injuries (TBIs) are a major public health issue,
post-concussion syndrome (PCS) remains a controversial entity. In both cases, the clinical …

[HTML][HTML] Salivary inflammatory biomarkers are predictive of mild cognitive impairment and Alzheimer's disease in a feasibility study

K McNicholas, M François, JW Liu… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is an insidious disease. Its distinctive pathology forms over a
considerable length of time without symptoms. There is a need to detect this disease, before …

Characterizing factors influencing baseline plasma biomarkers for sport-related concussion in adolescents

JB Tabor, LC Penner, JG Cooper, M Ghodsi… - Journal of …, 2023 - liebertpub.com
Developing objective measures to diagnose sport-related concussion (SRC) is a top priority,
particularly in the pediatric context, given the vulnerability of the developing brain. While …

Association between Serum Neurofilament Light and Glial Fibrillary Acidic Protein Levels and Head Impact Burden in Women's Collegiate Water Polo

ME Huibregtse, SH Sweeney, MR Stephens… - Journal of …, 2023 - liebertpub.com
Recent investigations have identified water polo athletes as at risk for concussions and
repetitive subconcussive head impacts. Head impact exposure in collegiate varsity women's …

[HTML][HTML] Calcium and Non-Penetrating Traumatic Brain Injury: A Proposal for the Implementation of an Early Therapeutic Treatment for Initial Head Insults

DH O'Day - Biomolecules, 2024 - mdpi.com
Finding an effective treatment for traumatic brain injury is challenging for multiple reasons.
There are innumerable different causes and resulting levels of damage for both penetrating …

Mind over Microbes: Investigating the Interplay between Lifestyle Factors, Gut Microbiota, and Brain Health

P Bali, P Lal, MS Sivapuram, LV Kutikuppala… - …, 2024 - karger.com
Background: The gut microbiota (GM) of the human body comprises several species of
microorganisms. This microorganism plays a significant role in the physiological and …

Acute Concussion

CJ Plummer, N Abramson - Physical Medicine and …, 2024 - pmr.theclinics.com
A concussion or mild traumatic brain injury (mTBI) is defined as a “traumatically induced
transient disturbance of brain function.” 1 The WHO (World Health Organization) defines …

Subconcussive head impacts sustained during American football alter gut microbiome diversity and composition

Z Pelland, A Zafar, A Ay, KD Belanger Jr - bioRxiv, 2024 - biorxiv.org
Subconcussive head impacts (SHIs) are a public health concern amongst at-risk
populations. SHIs are hits to the head that do not typically generate symptoms and are …

Impact of Fish Oil Supplementation on Plasma Levels of Fatty Acid-Containing Lipid Classes, Lipid Molecular Species, and Biomarkers of Brain Injury in Contact Sport …

VA Mullins - 2023 - search.proquest.com
Contact sports involve a high risk of concussive injury and a higher risk of injury from
repeated subconcussive head impacts (RSHI) that do not meet the threshold for a …