[HTML][HTML] Lung cancer immunotherapy: progress, pitfalls, and promises

A Lahiri, A Maji, PD Potdar, N Singh, P Parikh, B Bisht… - Molecular cancer, 2023 - Springer
Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy

J Guo, Y Zou, L Huang - Small Methods, 2023 - Wiley Online Library
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

ImmuCellAI-mouse: a tool for comprehensive prediction of mouse immune cell abundance and immune microenvironment depiction

YR Miao, M Xia, M Luo, T Luo, M Yang, AY Guo - Bioinformatics, 2022 - academic.oup.com
Motivation Immune cells are important components of the immune system and are crucial for
disease initiation, progression, prognosis and survival. Although several computational …

[HTML][HTML] The past, present, and future of breast cancer models for nanomedicine development

P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …

[HTML][HTML] Promising applications of tumor spheroids and organoids for personalized medicine

Z Gilazieva, A Ponomarev, C Rutland, A Rizvanov… - Cancers, 2020 - mdpi.com
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …

[HTML][HTML] Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models

MA Heinrich, AMRH Mostafa, JP Morton… - Advanced drug delivery …, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive type of cancer with
an overall survival rate of less than 7-8%, emphasizing the need for novel effective …

[HTML][HTML] Adoptive immunotherapy beyond CAR T-cells

A Titov, E Zmievskaya, I Ganeeva, A Valiullina… - Cancers, 2021 - mdpi.com
Simple Summary The aging of the world population leads to a constant increase of cancer-
related morbidity and mortality. Treatment of late-stage tumors has become a significant …

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Z Zeng, CJ Wong, L Yang, N Ouardaoui… - Nucleic acids …, 2022 - academic.oup.com
Syngeneic mouse models are tumors derived from murine cancer cells engrafted on
genetically identical mouse strains. They are widely used tools for studying tumor immunity …

[HTML][HTML] Immunocompetent cancer-on-chip models to assess immuno-oncology therapy

TI Maulana, E Kromidas, L Wallstabe… - Advanced Drug Delivery …, 2021 - Elsevier
The advances in cancer immunotherapy come with several obstacles, limiting its
widespread use and benefits so far only to a small subset of patients. One of the underlying …