[HTML][HTML] Psoriasis, cardiovascular events, and biologics: lights and shadows

G Caiazzo, G Fabbrocini, R Di Caprio… - Frontiers in …, 2018 - frontiersin.org
Nowadays, it is well established a link between psoriasis and cardiovascular (CV) diseases.
A series of different overlapping mechanisms including inflammation, homeostasis …

Chronic inflammation, cardiometabolic diseases and effects of treatment: psoriasis as a human model

M Aksentijevich, SS Lateef, P Anzenberg… - Trends in cardiovascular …, 2020 - Elsevier
Chronic inflammation in humans is associated with accelerated development of
cardiometabolic diseases such as myocardial infarction, stroke, and diabetes. Strong …

Severity of psoriasis associates with aortic vascular inflammation detected by FDG PET/CT and neutrophil activation in a prospective observational study

HB Naik, B Natarajan, E Stansky… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—To understand whether directly measured psoriasis severity is associated with
vascular inflammation assessed by 18F-fluorodeoxyglucose positron emission tomography …

[HTML][HTML] TNF-α antagonist and vascular inflammation in patients with psoriasis vulgaris: a randomized placebo-controlled study

R Bissonnette, F Harel, JG Krueger, MC Guertin… - Journal of Investigative …, 2017 - Elsevier
Vascular inflammation is increased in patients with psoriasis. This randomized, double-
blind, multicenter study evaluated the effects of tumor necrosis factor-α antagonist …

[HTML][HTML] Cardiometabolic comorbidities in patients with psoriasis: focusing on risk, biological therapy, and pathogenesis

J Cai, L Cui, Y Wang, Y Li, X Zhang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Psoriasis is a chronic inflammatory disease characterized by erythematous scaly plaques,
accompanied by systemic damage that leads to the development of multiple comorbidities …

Association between changes in coronary artery disease progression and treatment with biologic agents for severe psoriasis

KF Hjuler, M Bøttcher, C Vestergaard… - JAMA …, 2016 - jamanetwork.com
Importance Inflammatory pathways of psoriasis share similarities with the mechanisms
identified in atherosclerosis, and the association between psoriasis and cardiovascular …

[HTML][HTML] The risk of systemic diseases in those with psoriasis and psoriatic arthritis: from mechanisms to clinic

YR Woo, CJ Park, H Kang, JE Kim - International Journal of Molecular …, 2020 - mdpi.com
Psoriasis and psoriatic arthritis (PsA) have been recently considered as chronic systemic
inflammatory disorders. Over the past decades, enormous evidence indicates that patients …

Association of tumor necrosis factor inhibitor treatment with reduced indices of subclinical atherosclerosis in patients with psoriatic disease

L Eder, AA Joshi, AK Dey, R Cook… - Arthritis & …, 2018 - Wiley Online Library
Objective To assess the effect of tumor necrosis factor inhibitors (TNF i) on subclinical
cardiovascular disease in patients with psoriatic disease. Methods We performed a 2‐stage …

[HTML][HTML] Oxidative stress induced by high salt diet—possible implications for development and clinical manifestation of cutaneous inflammation and endothelial …

I Krajina, A Stupin, M Šola, M Mihalj - Antioxidants, 2022 - mdpi.com
Although oxidative stress is recognized as an important effector mechanism of the immune
system, uncontrolled formation of reactive oxygen and nitrogen species promotes excessive …

Practical recommendations for systemic treatment in psoriasis according to age, pregnancy, metabolic syndrome, mental health, psoriasis subtype and treatment …

JLW Lambert, S Segaert, PD Ghislain… - Journal of the …, 2020 - Wiley Online Library
Background Impressive progress in new therapeutic options has been made for psoriasis.
Treatments include topical steroids, phototherapy, conventional, synthetic disease …