Biomaterials to mimic and heal connective tissues

BR Freedman, DJ Mooney - Advanced Materials, 2019 - Wiley Online Library
Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

[PDF][PDF] Autologous fat or adipose-derived stem cell grafting in systemic sclerosis treatment: a systematic review and meta-analysis

Y Cao, H Kan, X Ma, Y Zhang, J Huang… - Clin Exp …, 2023 - clinexprheumatol.org
Objective Systemic sclerosis (SSc) is characterised by vasculopathy and progressive fibrosis
of the skin. The aim of this article is to analyse and summarise the efficacy and safety of …

Application of an iPSC‐derived organoid model for localized scleroderma therapy

J Ma, W Li, R Cao, D Gao, Q Zhang, X Li, B Li… - Advanced …, 2022 - Wiley Online Library
Localized scleroderma (LoS) is a rare chronic disease with extensive tissue fibrosis,
inflammatory infiltration, microvascular alterations, and epidermal appendage lesions …

Aesthetic and therapeutic outcome of fat grafting for localized Scleroderma treatment: From basic study to clinical application

HC Wang, R Dong, X Long… - Journal of Cosmetic …, 2021 - Wiley Online Library
Abstract Background Localized scleroderma (LoS) is a rare autoimmune disease
characterized by skin fibrosis and subcutaneous tissue atrophy, resulting in aesthetic …

Adipose-derived stem cells attenuate skin fibrosis and improve fat retention of a localized scleroderma mouse model

HC Wang, ET Sun, RC Zhao, B Chen… - Plastic and …, 2023 - journals.lww.com
Background: Although autologous fat grafting is a feasible surgical technique to improve
facial deformity in patients with localized scleroderma, its success is limited by the low graft …

Interventions for morphea

JV de Albuquerque, BNG Andriolo… - Cochrane Database …, 2019 - cochranelibrary.com
Background Morphea (morphoea) is an immune‐mediated disease in which excess
synthesis and deposition of collagen in the skin and underlying connective tissues results in …

Phototherapy for sclerosing skin conditions

NM Teske, HT Jacobe - Clinics in Dermatology, 2016 - Elsevier
Phototherapy is an effective treatment strategy for a variety of sclerosing skin conditions.
There are a number of phototherapeutic modalities used for the treatment of sclerosing skin …

[PDF][PDF] Granuloma annulare and morphea: correlation with Borrelia burgdorferi infections and Chlamydia-related bacteria

L Tolkki, K Hokynar, S Meri… - Acta Dermato …, 2018 - medicaljournalssweden.se
A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea
histology from patients with suspected tick bite was performed. Biopsies were tested for …

The development and initial validation of PUMC localized scleroderma facial aesthetic index: a pilot study

HC Wang, S Ling, X Wang, X Long, ET Sun, N Yu… - Aesthetic Plastic …, 2021 - Springer
Abstract Background Localized scleroderma (LoS) is an autoimmune connective tissue
disorder leading to serious long-term aesthetic impairment on patients. Objective evaluation …

[PDF][PDF] Morphea–selected local treatment methods and their effectiveness

J Narbutt, A Hołdrowicz, A Lesiak - Reumatologia/Rheumatology, 2017 - termedia.pl
Localised scleroderma is an uncommon connective tissue disease of multifactorial aetiology
occurring in the paediatric and adult population. It is relatively difficult to conduct any …