Non-coding RNA networks in cancer
E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
MicroRNA
TX Lu, ME Rothenberg - Journal of allergy and clinical immunology, 2018 - Elsevier
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …
Non-coding RNAs and potential therapeutic targeting in cancer
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
The emerging role of lncRNAs in cancer
M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …
that do not encode proteins. However, these regions are often transcribed into long …
[HTML][HTML] IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
The how and why of lncRNA function: an innate immune perspective
EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
INTRODUCTION The human genome contains tens of thousands of loci that produce long
noncoding RNAs (lncRNAs), transcripts that have no apparent protein-coding potential. A …
noncoding RNAs (lncRNAs), transcripts that have no apparent protein-coding potential. A …
Roles, functions, and mechanisms of long non-coding RNAs in cancer
Y Fang, MJ Fullwood - Genomics, Proteomics and …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
[HTML][HTML] The functions and unique features of LncRNAs in cancer development and tumorigenesis
K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
MicroRNAs as regulatory elements in immune system logic
A Mehta, D Baltimore - Nature Reviews Immunology, 2016 - nature.com
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …
decisions. They act by negatively regulating the expression of key immune development …