The endothelial angiopoietin (ANG)–TIE growth factor receptor pathway regulates vascular
permeability and pathological vascular remodelling during inflammation, tumour …

As angiogenesis is essential for tumor growth and metastasis, controlling tumor-associated
angiogenesis is a promising tactic in limiting cancer progression. The tumor …

The angiopoietin/Tie (ANG/Tie) receptor system controls developmental and tumor
angiogenesis, inflammatory vascular remodeling, and vessel leakage. ANG1 is a Tie2 …

We show that endothelial cell (EC)–generated vascular guidance tunnels (ie, matrix spaces
created during tube formation) serve as conduits for the recruitment and motility of pericytes …

Angiopoietins regulate vascular homeostasis via the endothelial Tie receptor tyrosine
kinases. Angiopoietin-1 (Ang1) supports endothelial stabilization via Tie2 activation …

Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult,
angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement …

During angiogenesis, αv integrins are overexpressed on the endothelial cell surface to
facilitate the growth and survival of newly forming vessels. Accordingly, blocking αv integrin …

Endothelial cells that form the inner layer of blood and lymphatic vessels are important
regulators of vascular functions and centrally involved in the pathogenesis of vascular …

Abstracts The Angiopoietin/Tie system acts as a vascular specific ligand/receptor system to
control endothelial cell survival and vascular maturation. The Angiopoietin family includes …

Angiopoietin-1 (Ang1) has powerful vascular protective effects: suppressing plasma
leakage, inhibiting vascular inflammation, and preventing endothelial death. Preclinical …