ctDNA guiding adjuvant immunotherapy in urothelial carcinoma

T Powles, ZJ Assaf, N Davarpanah, R Banchereau… - Nature, 2021 - nature.com
Minimally invasive approaches to detect residual disease after surgery are needed to
identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA …

Lymph node dissection in renal cell carcinoma

U Capitanio, F Becker, ML Blute, P Mulders, JJ Patard… - European urology, 2011 - Elsevier
CONTEXT: Although lymphadenectomy (lymph node dissection [LND]) is currently accepted
as the most accurate and reliable staging procedure for the detection of lymph node …

CT urography for hematuria

NC Cowan - Nature Reviews Urology, 2012 - nature.com
Hematuria can signify serious disease such as bladder cancer, upper urinary tract urothelial
cell carcinoma (UUT-UCC), renal cell cancer or urinary tract stones. CT urography is a …

Adjuvant atezolizumab versus observation in muscle-invasive urothelial carcinoma (IMvigor010): a multicentre, open-label, randomised, phase 3 trial

J Bellmunt, M Hussain, JE Gschwend, P Albers… - The Lancet …, 2021 - thelancet.com
Background Despite standard curative-intent treatment with neoadjuvant cisplatin-based
chemotherapy, followed by radical surgery in eligible patients, muscle-invasive urothelial …

International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: long-term results of the …

Journal of Clinical Oncology, 2011 - ascopubs.org
Purpose This article presents the long-term results of the international multicenter
randomized trial that investigated the use of neoadjuvant cisplatin, methotrexate, and …

[HTML][HTML] Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis

F Xie, Y Li, M Wang, C Huang, D Tao, F Zheng… - Molecular cancer, 2018 - Springer
Abstract Background Circular RNAs (circRNAs) are a new member of noncoding RNAs
(ncRNAs) that have recently been described as key regulators of gene expression. Our …

[HTML][HTML] An autophagy-related long non-coding RNA prognostic signature accurately predicts survival outcomes in bladder urothelial carcinoma patients

Z Sun, C Jing, C Xiao, T Li - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
In this study, we analyzed the prediction accuracy of an autophagy-related long non-coding
RNA (lncRNA) prognostic signature using bladder urothelial carcinoma (BLCA) patient data …

[HTML][HTML] Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer

WJ Kim, EJ Kim, SK Kim, YJ Kim, YS Ha, P Jeong… - Molecular cancer, 2010 - Springer
Background While several molecular markers of bladder cancer prognosis have been
identified, the limited value of current prognostic markers has created the need for new …

Updated overall survival by circulating tumor DNA status from the phase 3 IMvigor010 trial: adjuvant atezolizumab versus observation in muscle-invasive urothelial …

T Powles, ZJ Assaf, V Degaonkar, P Grivas, M Hussain… - European urology, 2024 - Elsevier
Abstract Background Interim results from IMvigor010 showed an overall survival (OS) benefit
for adjuvant atezolizumab (anti–PD-L1) versus observation in patients with circulating tumor …

Early and late perioperative outcomes following radical cystectomy: 90-day readmissions, morbidity and mortality in a contemporary series

CJ Stimson, SS Chang, DA Barocas… - The Journal of …, 2010 - auajournals.org
Purpose: Radical cystectomy remains associated with significant morbidity. Most series
report outcomes with relatively short-term followup that may underestimate the true …