Simple Summary Traditional preclinical testing, including 2D cell culture and animal models,
often fails to accurately predict drug efficacy in humans, especially for oncology drugs …

Comprehensive Summary Hydrogels are promising candidates for mimicking native
extracellular matrix (ECM) and are therefore widely adopted as scaffolds in tissue …

Plant roots are highly sensitive to physical stress in the soil, with appropriate mechanical
impedance promoting root elongation and lateral root growth. However, few studies have …

Healing of infected wounds has always been a challenge in clinical care. There is an urgent
need to develop an effective and economical wound dressing combining antimicrobial …

Hybrid structures made of natural-synthetic polymers have been interested due to high
biological features combining promising physical–mechanical properties. In this research, a …

The marine-derived hyaluronic acid and other natural biopolymers offer exciting possibilities
in the field of biomaterials, providing sustainable and biocompatible alternatives to synthetic …

Dysfunction of the central nervous system (CNS) following traumatic brain injuries (TBI),
spinal cord injuries (SCI), or strokes remains challenging to address using existing …

The microvascular network plays an important role in providing nutrients to the injured tissue
and exchanging various metabolites. However, how to achieve efficient penetration of the …

3D bioprinting is recognized as the ultimate additive biomanufacturing technology in tissue
engineering and regeneration, augmented with intelligent bioinks and bioprinters to …

Glaucoma valves (GVs) play an essential role in treating glaucoma. However, fibrosis after
implantation has limited their long-term success in clinical applications. In this study, we …