Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Age-associated changes to the mammalian DNA methylome are well documented and
thought to promote diseases of aging, such as cancer. Recent studies have identified …

Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic
role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG …

Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …

The number of age predictors based on DNA methylation (DNAm) profile is rising due to
their potential in predicting healthspan and application in age-related illnesses, such as …

Conditions and comorbidities of obesity mirror those of ageing and age‐related diseases.
Obesity and ageing share a similar spectrum of phenotypes such as compromised genomic …

Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Background Recent studies examining the association between posttraumatic stress
disorder (PTSD) and accelerated aging, as defined by DNA methylation-based estimates of …

Living longer is associated with an increased risk of chronic diseases, including impairments
of the musculoskeletal and immune system as well as metabolic disorders and certain …

A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …