Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …

Extensive degeneration of articular cartilage (AC) is a primary event in the pathogenesis of
osteoarthritis (OA) and other types of joint and bone inflammation. OA results in the loss of …

Owing to population aging, the social impact of osteoarthritis (OA)—the most common
musculoskeletal disease—is expected to increase dramatically. Yet, therapy is still limited to …

Objective To investigate the role of matrix metalloproteinase 13 (MMP‐13; collagenase 3) in
osteoarthritis (OA). Methods OA was surgically induced in the knees of MMP‐13–knockout …

Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

Objective. The aim of this study was to investigate the effect of endogenous matrix
metalloproteinases 2 and 9 (MMP-2 and MMP-9) on the invasive characteristics of RA …

Background Proteases, protease activity and inflammatory molecules in tears have been
found to be relevant in the pathogenesis of keratoconus. We sought to determine the …

Moringa oleifera, popularly known as a miracle tree or tree of life, has been extensively used
as a functional food and nutritional asset worldwide. Ethnomedicinal and traditional uses of …

It is now apparent that regulation of blood vessel growth contributes to the classical actions
of hormones on development, growth, and reproduction. Endothelial cells are ideally …

Matrix metalloproteinases (MMPs) are zinc-dependent enzymes. These enzymes play a
critical role in the destruction of articular cartilage in rheumatoid arthritis (RA), osteoarthritis …