A large body of evidence indicates that the presence of regulatory T cells (Tregs) in tumors is
associated with a dampened tumor-specific immune response and a clear negative impact …

The most frequent symptoms among the manifestations of cow milk protein allergy (CMPA)
are gastrointestinal. CMPA pathogenesis involves immunological mechanisms with …

A major challenge for human allogeneic islet transplantation is the development of effective
methods to induce donor-specific tolerance to obviate the need for life-long …

Dietary intervention with a unique prebiotic nondigestible carbohydrate mixture has been
shown to reduce the development of allergic disease in infants at risk. In this study, the …

purpose. To determine whether in vitro expanded CD4+ CD25+ Foxp3+ regulatory T cells
can suppress immune-mediated ocular surface inflammation in a mouse model of dry eye …

Background: It is well established that CD4+ CD25+ regulatory T (Treg) cells can modulate
allogeneic immune responses. Xenotransplantation, proposed as a means to address the …

Background. Intravenous immunoglobulins (IVIg) therapy is effective as a treatment for T-cell-
mediated immune diseases, but whether and how IVIg suppress allogeneic T-cell responses …

Several studies have shown that recipient-derived CD4+ CD25+ Foxp3+ regulatory T cells
(Tregs) are involved in transplantation tolerance. However, it is not clear whether allogeneic …

Dietary non-digestible carbohydrates reduce the development of cows' milk allergy in mice.
In the present study, the contribution of CD25+ regulatory T-cells (Treg) was investigated …

Many autoimmune diseases develop as a consequence of an altered balance between
autoreactive immune cells and suppressive FOXP3+ Treg. Restoring this balance through …