The role of machine learning and deep learning approaches for the detection of skin cancer

T Mazhar, I Haq, A Ditta, SAH Mohsan, F Rehman… - Healthcare, 2023 - mdpi.com
Machine learning (ML) can enhance a dermatologist's work, from diagnosis to customized
care. The development of ML algorithms in dermatology has been supported lately …

Fluorescent and phosphorescent nitrogen-containing heterocycles and crown ethers: biological and pharmaceutical applications

F Ullah, S Ullah, MFA Khan, M Mustaqeem… - Molecules, 2022 - mdpi.com
Fluorescent molecules absorb photons of specific wavelengths and emit a longer
wavelength photon within nanoseconds. Recently, fluorescent materials have been widely …

Anti-diabetic Activity of Brucine in Streptozotocin-Induced Rats: In Silico, In Vitro, and In Vivo Studies

NU Khan, NG Qazi, A Khan, F Ali, SS Hassan… - ACS …, 2022 - ACS Publications
Diabetes mellitus (DM) is a complex and multiple group of disorders, and understanding the
molecular mechanisms is a key role in identifying various markers involved in the diagnosis …

Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer's Disease

FJ Mirza, S Zahid, S Amber, H Jabeen, N Asim… - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) has been associated with the hallmark features of cholinergic
dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which …

Novel Isoxazole Derivative Attenuates Ethanol-Induced Gastric Mucosal Injury through Inhibition of H+/K+-ATPase Pump, Oxidative Stress and Inflammatory …

S Razzaq, AM Minhas, NG Qazi, H Nadeem, A Khan… - Molecules, 2022 - mdpi.com
Isoxazole derivatives are significant enough due to their wide range of pharmacological and
therapeutic activities. The purpose of the current study is to use computational, in vitro, in …

Therapeutic effects of Crataegus monogyna inhibitors against breast cancer

GM Basavarajappa, A Rehman… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is a silent killer disorder among women and a serious economic burden in
healthcare management. Every 19 s, a woman is diagnosed with breast cancer, and every …

Integrated bioinformatics-based subtractive genomics approach to decipher the therapeutic drug target and its possible intervention against brucellosis

K Khan, MSO Alhar, MN Abbas, SQ Abbas, M Kazi… - Bioengineering, 2022 - mdpi.com
Brucella suis, one of the causative agents of brucellosis, is Gram-negative intracellular
bacteria that may be found all over the globe and it is a significant facultative zoonotic …

[HTML][HTML] Mathematical modeling of cardio-oncology: modeling the systemic effects of cancer therapeutics on the cardiovascular system

CL Casson, SA John, MC Ferrall-Fairbanks - Seminars in Cancer Biology, 2023 - Elsevier
Cardiotoxicity is a common side-effect of many cancer therapeutics; however, to-date there
has been very little push to understand the mechanisms underlying this group of …

In-silico lead druggable compounds identification against SARS COVID-19 main protease target from in-house, chembridge and zinc databases by structure-based …

M Ghufran, M Ullah, HA Khan, S Ghufran, M Ayaz… - Bioengineering, 2023 - mdpi.com
Pharmacological strategies to lower the viral load among patients suffering from severe
diseases were researched in great detail during the SARS-CoV-2 outbreak. The viral …

Efficacy of 2-Hydroxyflavanone in rodent models of pain and inflammation: involvement of opioidergic and GABAergic anti-nociceptive mechanisms

FA Khan, G Ali, K Rahman, Y Khan, M Ayaz, OF Mosa… - Molecules, 2022 - mdpi.com
The current work examined the pharmacological potential of a selected flavanone derivative
2-hydroxyflavanone as a promising remedy for the treatment and management of pain. The …