Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas

OH Petersen, JV Gerasimenko… - Physiological …, 2021 - journals.physiology.org
This review deals with the roles of calcium ions and ATP in the control of the normal
functions of the different cell types in the exocrine pancreas as well as the roles of these …

Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

[HTML][HTML] Sitagliptin activates the p62–Keap1–Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute …

L Kong, J Deng, X Zhou, B Cai, B Zhang, X Chen… - Cell death & …, 2021 - nature.com
Acute lung injury (ALI) is a complication of severe acute pancreatitis (SAP). Sitagliptin (SIT)
is a DPP4 inhibitor that exerts anti-inflammatory and antioxidant effects; however, its …

Tetrahedral framework nucleic acids can alleviate taurocholate-induced severe acute pancreatitis and its subsequent multiorgan injury in mice

Y Wang, Y Li, S Gao, X Yu, Y Chen, Y Lin - Nano letters, 2022 - ACS Publications
Severe acute pancreatitis (SAP) is an inflammatory disease of the pancreas accompanied
by tissue injury and necrosis. It not only affects the pancreas but also triggers a systemic …

Microbiota in pancreatic health and disease: the next frontier in microbiome research

RM Thomas, C Jobin - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1
diabetes mellitus impart substantial health and financial burdens on society but identification …

[HTML][HTML] Tetramethylpyrazine: A review on its mechanisms and functions

J Lin, Q Wang, S Zhou, S Xu, K Yao - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely
used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid …

[HTML][HTML] Gut microbiota on admission as predictive biomarker for acute necrotizing pancreatitis

M Zou, Z Yang, Y Fan, L Gong, Z Han, L Ji… - Frontiers in …, 2022 - frontiersin.org
Background Acute necrotizing pancreatitis (NP), a severe form of acute pancreatitis (AP),
has higher mortality and worse outcome than non-necrotizing pancreatitis (non-NP). Infected …

Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis

R Fan, J Sui, X Dong, B Jing, Z Gao - Free Radical Biology and Medicine, 2021 - Elsevier
Acute pancreatitis (AP) is an inflammatory disorder associated with multiple organ failure.
Pyroptosis and ferroptosis are two newly recognized cell death, and whether pyroptosis and …

[HTML][HTML] Macrophages in pancreatitis: Mechanisms and therapeutic potential

F Hu, N Lou, J Jiao, F Guo, H Xiang, D Shang - Biomedicine & …, 2020 - Elsevier
Macrophages play a crucial role in the pathogenesis of pancreatitis that is a common
gastrointestinal disease. Particularly, macrophages differentiate into different phenotypes …