Purpose Apoptosis is an important physiological process, making a great difference to
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …

MicroRNAs (miRNAs) are small non-coding RNAs that alter the expression of target genes
at the post-transcriptional level, influencing diverse outcomes in metabolism, cell …

Osteoarthritis is a leading cause of disability in the world. The scientific literature highlights
the critical importance of epigenetic regulatory effects, intertwined with biomechanical and …

NUMB, a plasma membrane-associated protein originally described in Drosophila, is
involved in determining cell function and fate during early stages of development. It is …

Osteoarthritis (OA) is chronic arthritis characterized by articular cartilage degradation.
However, a comprehensive regulatory network for OA-related microRNAs and DNA …

Osteoarthritis is a multifactorial joint disease characterized by degeneration, and aging
stands as a significant risk factor. Autophagy, a crucial cellular homeostasis mechanism, is …

Osteoarthritis (OA) has been a leading cause of disability in the elderly and there remains a
lack of effective therapeutic approaches as the mechanisms of pathogenesis and …

Pain is a ubiquitous and highly concerned clinical symptom, usually caused by peripheral or
central nervous injury, tissue damage, or other diseases. The long-term existence of pain …

Introduction: Osteoarthritis (OA) is a degenerative disease common in the elderly and is
characterized by joint pain, swelling, and restricted movement. In recent years, heparanase …

Background MiR-146a has been widely studied in the pathogenesis of osteoarthritis (OA);
however, the results are still controversial. Objective This meta-analysis analyzes the …