Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Abstract High-grade gliomas (HGGs), including glioblastoma and diffuse intrinsic pontine
glioma, are amongst the most fatal brain tumors. These tumors are associated with a dismal …

Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Drug repurposing or repositioning has been well-known to refer to the therapeutic
applications of a drug for another indication other than it was originally approved for …

Cinnamic acids are compounds of natural origin that can be found in many different parts of
a wide panoply of plants, where they play the most diverse biological roles, often in a …

Background Breast cancer stem cells (BCSCs) have a critical role in progression of breast
cancer by inducing angiogenesis. Several therapeutic strategies have been designed for the …

Autophagy is a highly conserved metabolic process involved in the degradation of
intracellular components including proteins and organelles. Consequently, it plays a critical …

Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …

Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

A photocatalyzed cascade double C–C formation via sp2 C–H bond activation of
diarylamines with hypervalent iodine diazo reagents was developed. A variety of …